Human Gene Set: MEIOTIC_RECOMBINATION
Standard name
MEIOTIC_RECOMBINATION
Systematic name
M10539
Brief description
Genes annotated by the GO term GO:0007131. The cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.
Full description or abstract
Collection
ARCHIVED: Archived Founder gene sets that are referenced by current Hallmarks C5_GO: ARCHIVED Gene Ontology C5_GO:BP: ARCHIVED GO Biological Process
Source publication
Exact source
GO:0007131
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0007131
Filtered by similarity ?
Source species
Homo sapiens
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
HUMAN_GENE_SYMBOL
Dataset references
Download gene set
format: grp | gmt | xml | json | TSV metadata
Compute overlaps ?
Compendia expression profiles ?
Advanced query
Gene families ?
Show members
(show 17 source identifiers mapped to 17 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
ATM
472
ATM
ATM serine/threonine kinase [Source:HGNC Sym...
CHEK1
1111
CHEK1
checkpoint kinase 1 [Source:HGNC Symbol;Acc:...
DMC1
11144
DMC1
DNA meiotic recombinase 1 [Source:HGNC Symbo...
LIG3
3980
LIG3
DNA ligase 3 [Source:HGNC Symbol;Acc:HGNC:6600]
MRE11A
4361
MRE11
MRE11 homolog, double strand break repair nu...
MSH4
4438
MSH4
mutS homolog 4 [Source:HGNC Symbol;Acc:HGNC:...
MSH5
4439
MSH5
mutS homolog 5 [Source:HGNC Symbol;Acc:HGNC:...
RAD21
5885
RAD21
RAD21 cohesin complex component [Source:HGNC...
RAD50
10111
RAD50
RAD50 double strand break repair protein [So...
RAD51
5888
RAD51
RAD51 recombinase [Source:HGNC Symbol;Acc:HG...
RAD51L1
5890
RAD51B
RAD51 paralog B [Source:HGNC Symbol;Acc:HGNC...
RAD51L3
5892
RAD51D
RAD51 paralog D [Source:HGNC Symbol;Acc:HGNC...
RAD52
5893
RAD52
RAD52 homolog, DNA repair protein [Source:HG...
RAD54B
25788
RAD54B
RAD54 homolog B [Source:HGNC Symbol;Acc:HGNC...
REC8
9985
REC8
REC8 meiotic recombination protein [Source:H...
SPO11
23626
SPO11
SPO11 initiator of meiotic double strand bre...
SYCP1
6847
SYCP1
synaptonemal complex protein 1 [Source:HGNC ...
Version history
5.2: Archived
Gene set replaced by GOBP_HOMOLOGOUS_RECOMBINATION
See MSigDB license terms here . Please note that certain gene sets
have special access terms.