Human Gene Set: KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY


Standard name KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY
Systematic name M47751
Brief description Pathway Definition from KEGG: SIGMAR1* -> ITPR -> Ca2+ -- MCU -> Ca2+(mito) -- MPTP -> CYCS
Full description or abstract Mutation-inactivated SIGMAR1 to Ca2+ -apoptotic pathway. Pathway ID: N01151. Pathway type: Variant. Pathway class: nt06464 Amyotrophic lateral sclerosis.
Collection C2: Curated
      CP: Canonical Pathways
            CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication  
Exact source N01151
Related gene sets  
External links https://www.kegg.jp/entry/N01151
Filtered by similarity ?
Source species Homo sapiens
Contributed by KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 13 genes
Gene families ? Categorize these 13 genes by gene family
Show members (show 13 source identifiers mapped to 13 genes)
Version history 2024.1.Hs: Updated to network file downloaded on 2024-05-27

See MSigDB license terms here. Please note that certain gene sets have special access terms.