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Human Gene Set: KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY
Systematic name
M49000
Brief description
Pathway Definition from KEGG: PRKN* -> PLCG1 -> IP3 -> ITPR -> Ca2+
Full description or abstract
Mutation-inactivated PRKN to mGluR1 signaling pathway. Pathway ID: N01032. Pathway type: Variant. Pathway class: nt06463 Parkinson disease.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01032
Related gene sets
External links
https://www.kegg.jp/entry/N01032
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
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these 5 genes
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Show members
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5 source identifiers mapped to 5 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
3708
3708
ITPR1
inositol 1,4,5-trisphosphate receptor type 1 [Sou...
3709
3709
ITPR2
inositol 1,4,5-trisphosphate receptor type 2 [Sou...
3710
3710
ITPR3
inositol 1,4,5-trisphosphate receptor type 3 [Sou...
5071
5071
PRKN
parkin RBR E3 ubiquitin protein ligase [Source:HG...
5335
5335
PLCG1
phospholipase C gamma 1 [Source:HGNC Symbol;Acc:H...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-334
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