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Human Gene Set: KEGG_MEDICUS_VARIANT_HRAS_OVEREXPRESSION_TO_ERK_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_VARIANT_HRAS_OVEREXPRESSION_TO_ERK_SIGNALING_PATHWAY
Systematic name
M47420
Brief description
Pathway Definition from KEGG: HRAS* -> RAF -> MEK -> ERK -> MSK1 -> MYC
Full description or abstract
HRAS-overexpression to ERK signaling pathway. Pathway ID: N00077. Pathway type: Variant. Pathway class: nt06265 Bladder cancer.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N00077
Related gene sets
External links
https://www.kegg.jp/entry/N00077
Filtered by similarity
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1 similar term(s) from the external resource)
External ID
External Name
N00078
Mutation-activated HRAS to ERK signaling pathway
Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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json
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
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these 10 genes
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Show members
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10 source identifiers mapped to 10 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
3265
3265
HRAS
HRas proto-oncogene, GTPase [Source:HGNC Symbol...
369
369
ARAF
A-Raf proto-oncogene, serine/threonine kinase [...
4609
4609
MYC
MYC proto-oncogene, bHLH transcription factor [...
5594
5594
MAPK1
mitogen-activated protein kinase 1 [Source:HGNC...
5595
5595
MAPK3
mitogen-activated protein kinase 3 [Source:HGNC...
5604
5604
MAP2K1
mitogen-activated protein kinase kinase 1 [Sour...
5605
5605
MAP2K2
mitogen-activated protein kinase kinase 2 [Sour...
5894
5894
RAF1
Raf-1 proto-oncogene, serine/threonine kinase [...
673
673
BRAF
B-Raf proto-oncogene, serine/threonine kinase [...
9252
9252
RPS6KA5
ribosomal protein S6 kinase A5 [Source:HGNC Sym...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-641
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