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Human Gene Set: KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_CELL_CYCLE_G1_S
Standard name
KEGG_MEDICUS_VARIANT_AMPLIFIED_MYC_TO_CELL_CYCLE_G1_S
Systematic name
M47426
Brief description
Pathway Definition from KEGG: (MYC*+MAX) => (CCND+CDK4/6) -> RB1 // E2F
Full description or abstract
Amplified MYC to cell cycle G1/S. Pathway ID: N00089. Pathway type: Variant. Pathway class: nt06267 Small cell lung cancer.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N00089
Related gene sets
External links
https://www.kegg.jp/entry/N00089
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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json
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 11 genes
Gene families
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Show members
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show
11 source identifiers mapped to 11 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
1019
1019
CDK4
cyclin dependent kinase 4 [Source:HGNC Symbol;Acc...
1021
1021
CDK6
cyclin dependent kinase 6 [Source:HGNC Symbol;Acc...
1869
1869
E2F1
E2F transcription factor 1 [Source:HGNC Symbol;Ac...
1870
1870
E2F2
E2F transcription factor 2 [Source:HGNC Symbol;Ac...
1871
1871
E2F3
E2F transcription factor 3 [Source:HGNC Symbol;Ac...
4149
4149
MAX
MYC associated factor X [Source:HGNC Symbol;Acc:H...
4609
4609
MYC
MYC proto-oncogene, bHLH transcription factor [So...
5925
5925
RB1
RB transcriptional corepressor 1 [Source:HGNC Sym...
595
595
CCND1
cyclin D1 [Source:HGNC Symbol;Acc:HGNC:1582]
894
894
CCND2
cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583]
896
896
CCND3
cyclin D3 [Source:HGNC Symbol;Acc:HGNC:1585]
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-314
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