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Human Gene Set: KEGG_MEDICUS_REFERENCE_TNF_RIPK1_3_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_REFERENCE_TNF_RIPK1_3_SIGNALING_PATHWAY
Systematic name
M47944
Brief description
Pathway Definition from KEGG: TNF -> TNFRSF1A -> (TRAF2/5+TRADD+RIPK1+RIPK3)
Full description or abstract
TNF-RIPK1/3 signaling pathway. Pathway ID: N01621. Pathway type: Reference. Pathway class: nt06527 Necroptosis.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01621
Related gene sets
External links
https://www.kegg.jp/entry/N01621
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
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these 7 genes
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Show members
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7 source identifiers mapped to 7 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
11035
11035
RIPK3
receptor interacting serine/threonine kinase...
7124
7124
TNF
tumor necrosis factor [Source:HGNC Symbol;Ac...
7132
7132
TNFRSF1A
TNF receptor superfamily member 1A [Source:H...
7186
7186
TRAF2
TNF receptor associated factor 2 [Source:HGN...
7188
7188
TRAF5
TNF receptor associated factor 5 [Source:HGN...
8717
8717
TRADD
TNFRSF1A associated via death domain [Source...
8737
8737
RIPK1
receptor interacting serine/threonine kinase...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-507
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