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Human Gene Set: KEGG_MEDICUS_REFERENCE_TLR3_NFKB_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_REFERENCE_TLR3_NFKB_SIGNALING_PATHWAY
Systematic name
M47601
Brief description
Pathway Definition from KEGG: TLR3 -> TICAM1 -> TRAF6 -> TAK1 -> IKK -> NFKBIA -> NFKB
Full description or abstract
TLR3-NFKB signaling pathway. Pathway ID: N00563. Pathway type: Reference. Pathway class: nt06168 Herpes simplex virus 1 (HSV-1).
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N00563
Related gene sets
External links
https://www.kegg.jp/entry/N00563
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
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Show members
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10 source identifiers mapped to 10 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
1147
1147
CHUK
component of inhibitor of nuclear factor kap...
148022
148022
TICAM1
TIR domain containing adaptor molecule 1 [So...
3551
3551
IKBKB
inhibitor of nuclear factor kappa B kinase s...
4790
4790
NFKB1
nuclear factor kappa B subunit 1 [Source:HGN...
4792
4792
NFKBIA
NFKB inhibitor alpha [Source:HGNC Symbol;Acc...
5970
5970
RELA
RELA proto-oncogene, NF-kB subunit [Source:H...
6885
6885
MAP3K7
mitogen-activated protein kinase kinase kina...
7098
7098
TLR3
toll like receptor 3 [Source:HGNC Symbol;Acc...
7189
7189
TRAF6
TNF receptor associated factor 6 [Source:HGN...
8517
8517
IKBKG
inhibitor of nuclear factor kappa B kinase r...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-503
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