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Human Gene Set: KEGG_MEDICUS_REFERENCE_TESTOSTERONE_BIOSYNTHESIS
Standard name
KEGG_MEDICUS_REFERENCE_TESTOSTERONE_BIOSYNTHESIS
Systematic name
M47895
Brief description
Pathway Definition from KEGG: Pregnenolone -- CYP17A1 >> HSD3B1/2 -> Androstenedione -- (AKR1C3,HSD17B) -> T -- SRD5A -> DHT
Full description or abstract
Testosterone biosynthesis. Pathway ID: N01541. Pathway type: Reference. Pathway class: nt06019 Steroid hormone biosynthesis.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01541
Related gene sets
External links
https://www.kegg.jp/entry/N01541
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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json
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
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NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 11 genes
Gene families
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Show members
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11 source identifiers mapped to 11 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
1586
1586
CYP17A1
cytochrome P450 family 17 subfamily A member ...
3283
3283
HSD3B1
hydroxy-delta-5-steroid dehydrogenase, 3 beta...
3284
3284
HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta...
3293
3293
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3 [Sourc...
3294
3294
HSD17B2
hydroxysteroid 17-beta dehydrogenase 2 [Sourc...
6715
6715
SRD5A1
steroid 5 alpha-reductase 1 [Source:HGNC Symb...
6716
6716
SRD5A2
steroid 5 alpha-reductase 2 [Source:HGNC Symb...
7923
7923
HSD17B8
hydroxysteroid 17-beta dehydrogenase 8 [Sourc...
79644
79644
SRD5A3
steroid 5 alpha-reductase 3 [Source:HGNC Symb...
8630
8630
HSD17B6
hydroxysteroid 17-beta dehydrogenase 6 [Sourc...
8644
8644
AKR1C3
aldo-keto reductase family 1 member C3 [Sourc...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-79
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