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Human Gene Set: KEGG_MEDICUS_REFERENCE_RAC_CDC42_PAK_ERK_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_REFERENCE_RAC_CDC42_PAK_ERK_SIGNALING_PATHWAY
Systematic name
M47735
Brief description
Pathway Definition from KEGG: (RAC1,CDC42) -> PAK1 -> RAF -> MEK -> ERK
Full description or abstract
RAC/CDC42-PAK-ERK signaling pathway. Pathway ID: N01119. Pathway type: Reference. Pathway class: nt06526 MAPK signaling.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01119
Related gene sets
External links
https://www.kegg.jp/entry/N01119
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
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Show members
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10 source identifiers mapped to 10 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
369
369
ARAF
A-Raf proto-oncogene, serine/threonine kinase [S...
5058
5058
PAK1
p21 (RAC1) activated kinase 1 [Source:HGNC Symbo...
5594
5594
MAPK1
mitogen-activated protein kinase 1 [Source:HGNC ...
5595
5595
MAPK3
mitogen-activated protein kinase 3 [Source:HGNC ...
5604
5604
MAP2K1
mitogen-activated protein kinase kinase 1 [Sourc...
5605
5605
MAP2K2
mitogen-activated protein kinase kinase 2 [Sourc...
5879
5879
RAC1
Rac family small GTPase 1 [Source:HGNC Symbol;Ac...
5894
5894
RAF1
Raf-1 proto-oncogene, serine/threonine kinase [S...
673
673
BRAF
B-Raf proto-oncogene, serine/threonine kinase [S...
998
998
CDC42
cell division cycle 42 [Source:HGNC Symbol;Acc:H...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-420
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