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Human Gene Set: KEGG_MEDICUS_REFERENCE_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION
Standard name
KEGG_MEDICUS_REFERENCE_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION
Systematic name
M47742
Brief description
Pathway Definition from KEGG: PINK1 -> PRKN -> (CISD1,CISD2,FAF2,FKBP8,TOMM70,HK1) == (SQSTM1,OPTN,NDP52,TAX1BP1,NBR1) == LC3
Full description or abstract
PINK-Parkin-mediated autophagosome formation. Pathway ID: N01137. Pathway type: Reference. Pathway class: nt06464 Amyotrophic lateral sclerosis.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01137
Related gene sets
External links
https://www.kegg.jp/entry/N01137
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
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grp
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 17 genes
Gene families
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Show members
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17 source identifiers mapped to 17 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
10133
10133
OPTN
optineurin [Source:HGNC Symbol;Acc:HGNC:1...
10241
10241
CALCOCO2
calcium binding and coiled-coil domain 2 ...
23197
23197
FAF2
Fas associated factor family member 2 [So...
23770
23770
FKBP8
FKBP prolyl isomerase 8 [Source:HGNC Symb...
3098
3098
HK1
hexokinase 1 [Source:HGNC Symbol;Acc:HGNC...
4077
4077
NBR1
NBR1 autophagy cargo receptor [Source:HGN...
440738
440738
MAP1LC3C
microtubule associated protein 1 light ch...
493856
493856
CISD2
CDGSH iron sulfur domain 2 [Source:HGNC S...
5071
5071
PRKN
parkin RBR E3 ubiquitin protein ligase [S...
55847
55847
CISD1
CDGSH iron sulfur domain 1 [Source:HGNC S...
643246
643246
MAP1LC3B2
microtubule associated protein 1 light ch...
65018
65018
PINK1
PTEN induced kinase 1 [Source:HGNC Symbol...
81631
81631
MAP1LC3B
microtubule associated protein 1 light ch...
84557
84557
MAP1LC3A
microtubule associated protein 1 light ch...
8878
8878
SQSTM1
sequestosome 1 [Source:HGNC Symbol;Acc:HG...
8887
8887
TAX1BP1
Tax1 binding protein 1 [Source:HGNC Symbo...
9868
9868
TOMM70
translocase of outer mitochondrial membra...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-464
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