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Human Gene Set: KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY
Systematic name
M47423
Brief description
Pathway Definition from KEGG: (DLL,JAG) -> NOTCH -> (NICD+RBPJ) => (HES1,HEY1)
Full description or abstract
Notch signaling pathway. Pathway ID: N00086. Pathway type: Reference. Pathway class: nt06511 NOTCH signaling.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N00086
Related gene sets
External links
https://www.kegg.jp/entry/N00086
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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json
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TSV metadata
Compute overlaps
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 13 genes
Gene families
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Categorize
these 13 genes by gene family
Show members
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show
13 source identifiers mapped to 13 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
10683
10683
DLL3
delta like canonical Notch ligand 3 [Source:HG...
11317
11317
RBPJL
recombination signal binding protein for immun...
182
182
JAG1
jagged canonical Notch ligand 1 [Source:HGNC S...
23462
23462
HEY1
hes related family bHLH transcription factor w...
28514
28514
DLL1
delta like canonical Notch ligand 1 [Source:HG...
3280
3280
HES1
hes family bHLH transcription factor 1 [Source...
3516
3516
RBPJ
recombination signal binding protein for immun...
3714
3714
JAG2
jagged canonical Notch ligand 2 [Source:HGNC S...
4851
4851
NOTCH1
notch receptor 1 [Source:HGNC Symbol;Acc:HGNC:...
4853
4853
NOTCH2
notch receptor 2 [Source:HGNC Symbol;Acc:HGNC:...
4854
4854
NOTCH3
notch receptor 3 [Source:HGNC Symbol;Acc:HGNC:...
4855
4855
NOTCH4
notch receptor 4 [Source:HGNC Symbol;Acc:HGNC:...
54567
54567
DLL4
delta like canonical Notch ligand 4 [Source:HG...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-204
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