login
register
GSEA Home
Downloads
Molecular Signatures Database
Documentation
Contact
Team
MSigDB Home
Human Collections
About
Browse
Search
Investigate
Gene Families
Mouse Collections
About
Browse
Search
Investigate
Help
Human Gene Set: KEGG_MEDICUS_REFERENCE_LYSOSOMAL_CA2_RELEASE
Standard name
KEGG_MEDICUS_REFERENCE_LYSOSOMAL_CA2_RELEASE
Systematic name
M47954
Brief description
Pathway Definition from KEGG: PI(3.5)P2 -> MCOLN1 -> Ca2+(cyto) -> CALM == CN -> TFEB
Full description or abstract
Lysosomal Ca2+ release. Pathway ID: N01644. Pathway type: Reference. Pathway class: nt06528 Calcium signaling.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01644
Related gene sets
External links
https://www.kegg.jp/entry/N01644
Filtered by similarity
?
Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
|
gmt
|
xml
|
json
|
TSV metadata
Compute overlaps
?
(
show
collections to investigate for overlap with this gene set)
H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
?
NG-CHM interactive heatmaps
(
Please note that clustering takes a few seconds
)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 10 genes
Gene families
?
Categorize
these 10 genes by gene family
Show members
(
show
10 source identifiers mapped to 10 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
5530
5530
PPP3CA
protein phosphatase 3 catalytic subunit alpha ...
5532
5532
PPP3CB
protein phosphatase 3 catalytic subunit beta [...
5533
5533
PPP3CC
protein phosphatase 3 catalytic subunit gamma ...
5534
5534
PPP3R1
protein phosphatase 3 regulatory subunit B, al...
5535
5535
PPP3R2
protein phosphatase 3 regulatory subunit B, be...
57192
57192
MCOLN1
mucolipin TRP cation channel 1 [Source:HGNC Sy...
7942
7942
TFEB
transcription factor EB [Source:HGNC Symbol;Ac...
801
801
CALM1
calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442]
805
805
CALM2
calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445]
808
808
CALM3
calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449]
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-407
See
MSigDB license terms here
. Please note that certain gene sets have special access terms.