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Human Gene Set: KEGG_MEDICUS_REFERENCE_LESION_BYPASS_BY_TLS_AND_DSB_FORMATION
Standard name
KEGG_MEDICUS_REFERENCE_LESION_BYPASS_BY_TLS_AND_DSB_FORMATION
Systematic name
M47854
Brief description
Pathway Definition from KEGG: FANCD2+FANCI+Ub -> FAN1 == SLX+MUS81+EME1 == ERCC4+ERCC1+SNM1A -> REV1,REV3L,REV7
Full description or abstract
Lesion bypass by TLS and DSB formation. Pathway ID: N01465. Pathway type: Reference. Pathway class: nt06508 Interstrand crosslink repair.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01465
Related gene sets
External links
https://www.kegg.jp/entry/N01465
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
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Show members
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15 source identifiers mapped to 15 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
10459
10459
MAD2L2
mitotic arrest deficient 2 like 2 [Source:H...
146956
146956
EME1
essential meiotic structure-specific endonu...
2067
2067
ERCC1
ERCC excision repair 1, endonuclease non-ca...
2072
2072
ERCC4
ERCC excision repair 4, endonuclease cataly...
2177
2177
FANCD2
FA complementation group D2 [Source:HGNC Sy...
22909
22909
FAN1
FANCD2 and FANCI associated nuclease 1 [Sou...
51455
51455
REV1
REV1 DNA directed polymerase [Source:HGNC S...
548593
548593
SLX1A
SLX1 homolog A, structure-specific endonucl...
55215
55215
FANCI
FA complementation group I [Source:HGNC Sym...
5980
5980
REV3L
REV3 like, DNA directed polymerase zeta cat...
7314
7314
UBB
ubiquitin B [Source:HGNC Symbol;Acc:HGNC:12...
79008
79008
SLX1B
SLX1 homolog B, structure-specific endonucl...
80198
80198
MUS81
MUS81 structure-specific endonuclease subun...
84464
84464
SLX4
SLX4 structure-specific endonuclease subuni...
9937
9937
DCLRE1A
DNA cross-link repair 1A [Source:HGNC Symbo...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-138
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