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Human Gene Set: KEGG_MEDICUS_REFERENCE_IL10_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_REFERENCE_IL10_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY
Systematic name
M47556
Brief description
Pathway Definition from KEGG: (IL10,IL19,IL20,IL22,IL24,IL26) -> ((IL10RB+(IL10RA,IL20RA,IL22RA1)) -> (JAK1+TYK2) -> STAT3
Full description or abstract
IL10 family to Jak-STAT signaling pathway. Pathway ID: N00415. Pathway type: Reference. Pathway class: nt06518 JAK-STAT signaling.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N00415
Related gene sets
External links
https://www.kegg.jp/entry/N00415
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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xml
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 13 genes
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Show members
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13 source identifiers mapped to 13 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
11009
11009
IL24
interleukin 24 [Source:HGNC Symbol;Acc:HGNC:1...
29949
29949
IL19
interleukin 19 [Source:HGNC Symbol;Acc:HGNC:5...
3586
3586
IL10
interleukin 10 [Source:HGNC Symbol;Acc:HGNC:5...
3587
3587
IL10RA
interleukin 10 receptor subunit alpha [Source...
3588
3588
IL10RB
interleukin 10 receptor subunit beta [Source:...
3716
3716
JAK1
Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6...
50604
50604
IL20
interleukin 20 [Source:HGNC Symbol;Acc:HGNC:6...
50616
50616
IL22
interleukin 22 [Source:HGNC Symbol;Acc:HGNC:1...
53832
53832
IL20RA
interleukin 20 receptor subunit alpha [Source...
55801
55801
IL26
interleukin 26 [Source:HGNC Symbol;Acc:HGNC:1...
58985
58985
IL22RA1
interleukin 22 receptor subunit alpha 1 [Sour...
6774
6774
STAT3
signal transducer and activator of transcript...
7297
7297
TYK2
tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGN...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-275
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