login
register
GSEA Home
Downloads
Molecular Signatures Database
Documentation
Contact
Team
MSigDB Home
Human Collections
About
Browse
Search
Investigate
Gene Families
Mouse Collections
About
Browse
Search
Investigate
Help
Human Gene Set: KEGG_MEDICUS_REFERENCE_HIF_1_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_REFERENCE_HIF_1_SIGNALING_PATHWAY
Systematic name
M47421
Brief description
Pathway Definition from KEGG: HIF1A == ARNT => (SLC2A1,VEGFA,TGFB,PDGFB,TGFA)
Full description or abstract
HIF-1 signaling pathway. Pathway ID: N00079. Pathway type: Reference. Pathway class: nt06264 Renal cell carcinoma.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N00079
Related gene sets
External links
https://www.kegg.jp/entry/N00079
Filtered by similarity
?
Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
|
gmt
|
xml
|
json
|
TSV metadata
Compute overlaps
?
(
show
collections to investigate for overlap with this gene set)
H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
?
NG-CHM interactive heatmaps
(
Please note that clustering takes a few seconds
)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 9 genes
Gene families
?
Categorize
these 9 genes by gene family
Show members
(
show
9 source identifiers mapped to 9 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
3091
3091
HIF1A
hypoxia inducible factor 1 subunit alpha [Source...
405
405
ARNT
aryl hydrocarbon receptor nuclear translocator [...
5155
5155
PDGFB
platelet derived growth factor subunit B [Source...
6513
6513
SLC2A1
solute carrier family 2 member 1 [Source:HGNC Sy...
7039
7039
TGFA
transforming growth factor alpha [Source:HGNC Sy...
7040
7040
TGFB1
transforming growth factor beta 1 [Source:HGNC S...
7042
7042
TGFB2
transforming growth factor beta 2 [Source:HGNC S...
7043
7043
TGFB3
transforming growth factor beta 3 [Source:HGNC S...
7422
7422
VEGFA
vascular endothelial growth factor A [Source:HGN...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-232
See
MSigDB license terms here
. Please note that certain gene sets have special access terms.