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Human Gene Set: KEGG_MEDICUS_REFERENCE_HGF_MET_PI3K_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_REFERENCE_HGF_MET_PI3K_SIGNALING_PATHWAY
Systematic name
M47401
Brief description
Pathway Definition from KEGG: HGF -> MET -> GAB1 -> PI3K -> PIP3 -> AKT -| BAD
Full description or abstract
HGF-MET-PI3K signaling pathway. Pathway ID: N00043. Pathway type: Reference. Pathway class: nt06261 Gastric cancer.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N00043
Related gene sets
External links
https://www.kegg.jp/entry/N00043
Filtered by similarity
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1 similar term(s) from the external resource)
External ID
External Name
N00247
HGF-overexpression to PI3K signaling pathway
Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
|
gmt
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xml
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json
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 10 genes
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Show members
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10 source identifiers mapped to 10 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
10000
10000
AKT3
AKT serine/threonine kinase 3 [Source:HGNC Sym...
207
207
AKT1
AKT serine/threonine kinase 1 [Source:HGNC Sym...
208
208
AKT2
AKT serine/threonine kinase 2 [Source:HGNC Sym...
2549
2549
GAB1
GRB2 associated binding protein 1 [Source:HGNC...
3082
3082
HGF
hepatocyte growth factor [Source:HGNC Symbol;A...
4233
4233
MET
MET proto-oncogene, receptor tyrosine kinase [...
5290
5290
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase...
5291
5291
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase...
5293
5293
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase...
572
572
BAD
BCL2 associated agonist of cell death [Source:...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-638
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