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Human Gene Set: KEGG_MEDICUS_REFERENCE_FLCN_MTORC1_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_REFERENCE_FLCN_MTORC1_SIGNALING_PATHWAY
Systematic name
M47922
Brief description
Pathway Definition from KEGG: (SLC7A5+SLC3A2) -> FLCN -> (RRAGA+RRAGB+RRAGC+RRAGD) -> mTORC1
Full description or abstract
FLCN-mTORC1 signaling pathway. Pathway ID: N01584. Pathway type: Reference. Pathway class: nt06522 mTOR signaling.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01584
Related gene sets
External links
https://www.kegg.jp/entry/N01584
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
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grp
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 14 genes
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Show members
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14 source identifiers mapped to 14 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
10325
10325
RRAGB
Ras related GTP binding B [Source:HGNC Symbo...
10670
10670
RRAGA
Ras related GTP binding A [Source:HGNC Symbo...
201163
201163
FLCN
folliculin [Source:HGNC Symbol;Acc:HGNC:27310]
2475
2475
MTOR
mechanistic target of rapamycin kinase [Sour...
57521
57521
RPTOR
regulatory associated protein of MTOR comple...
58528
58528
RRAGD
Ras related GTP binding D [Source:HGNC Symbo...
64121
64121
RRAGC
Ras related GTP binding C [Source:HGNC Symbo...
64223
64223
MLST8
MTOR associated protein, LST8 homolog [Sourc...
64798
64798
DEPTOR
DEP domain containing MTOR interacting prote...
6520
6520
SLC3A2
solute carrier family 3 member 2 [Source:HGN...
8140
8140
SLC7A5
solute carrier family 7 member 5 [Source:HGN...
84335
84335
AKT1S1
AKT1 substrate 1 [Source:HGNC Symbol;Acc:HGN...
9675
9675
TTI1
TELO2 interacting protein 1 [Source:HGNC Sym...
9894
9894
TELO2
telomere maintenance 2 [Source:HGNC Symbol;A...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-561
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