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Human Gene Set: KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CALCINEURIN_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CALCINEURIN_SIGNALING_PATHWAY
Systematic name
M47449
Brief description
Pathway Definition from KEGG: EGF -> EGFR -> PLCG -> IP3 -> Ca2+ -> CALM == CN -> NFAT
Full description or abstract
EGF-EGFR-PLCG-calcineurin signaling pathway. Pathway ID: N00147. Pathway type: Reference. Pathway class: nt06220 Calcium signaling.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N00147
Related gene sets
External links
https://www.kegg.jp/entry/N00147
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 16 genes
Gene families
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Show members
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16 source identifiers mapped to 16 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
1950
1950
EGF
epidermal growth factor [Source:HGNC Symbol;Acc:...
1956
1956
EGFR
epidermal growth factor receptor [Source:HGNC Sy...
4772
4772
NFATC1
nuclear factor of activated T cells 1 [Source:HG...
4773
4773
NFATC2
nuclear factor of activated T cells 2 [Source:HG...
4775
4775
NFATC3
nuclear factor of activated T cells 3 [Source:HG...
4776
4776
NFATC4
nuclear factor of activated T cells 4 [Source:HG...
5335
5335
PLCG1
phospholipase C gamma 1 [Source:HGNC Symbol;Acc:...
5336
5336
PLCG2
phospholipase C gamma 2 [Source:HGNC Symbol;Acc:...
5530
5530
PPP3CA
protein phosphatase 3 catalytic subunit alpha [S...
5532
5532
PPP3CB
protein phosphatase 3 catalytic subunit beta [So...
5533
5533
PPP3CC
protein phosphatase 3 catalytic subunit gamma [S...
5534
5534
PPP3R1
protein phosphatase 3 regulatory subunit B, alph...
5535
5535
PPP3R2
protein phosphatase 3 regulatory subunit B, beta...
801
801
CALM1
calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442]
805
805
CALM2
calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445]
808
808
CALM3
calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449]
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-109
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