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Human Gene Set: KEGG_MEDICUS_REFERENCE_CXCR4_GNA12_13_RHO_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_REFERENCE_CXCR4_GNA12_13_RHO_SIGNALING_PATHWAY
Systematic name
M47546
Brief description
Pathway Definition from KEGG: CXCL12 -> CXCR4 -> GNA12/13 -> (ARHGEF12,ARHGEF1) -> RHOA -> ROCK1/2
Full description or abstract
CXCR4-GNA12/13-Rho signaling pathway. Pathway ID: N00405. Pathway type: Reference. Pathway class: nt06167 Human cytomegalovirus (HCMV).
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N00405
Related gene sets
External links
https://www.kegg.jp/entry/N00405
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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json
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
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these 9 genes
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Show members
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9 source identifiers mapped to 9 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
10672
10672
GNA13
G protein subunit alpha 13 [Source:HGNC Symb...
23365
23365
ARHGEF12
Rho guanine nucleotide exchange factor 12 [S...
2768
2768
GNA12
G protein subunit alpha 12 [Source:HGNC Symb...
387
387
RHOA
ras homolog family member A [Source:HGNC Sym...
6093
6093
ROCK1
Rho associated coiled-coil containing protei...
6387
6387
CXCL12
C-X-C motif chemokine ligand 12 [Source:HGNC...
7852
7852
CXCR4
C-X-C motif chemokine receptor 4 [Source:HGN...
9138
9138
ARHGEF1
Rho guanine nucleotide exchange factor 1 [So...
9475
9475
ROCK2
Rho associated coiled-coil containing protei...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-445
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