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Human Gene Set: KEGG_MEDICUS_REFERENCE_CHOLESTEROL_BIOSYNTHESIS
Standard name
KEGG_MEDICUS_REFERENCE_CHOLESTEROL_BIOSYNTHESIS
Systematic name
M47945
Brief description
Pathway Definition from KEGG: Farnesyl-PP -- FDFT1 >> SQLE >> LSS >> CYP51A1 >> (TM7SF2,LBR) >> MSMO1 >> NSDHL >> HSD17B7 >> DHCR24 >> EBP >> SC5D -> 7-DHC -- DHCR7 -> Cholesterol
Full description or abstract
Cholesterol biosynthesis. Pathway ID: N01624. Pathway type: Reference. Pathway class: nt06034 Cholesterol biosynthesis.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01624
Related gene sets
External links
https://www.kegg.jp/entry/N01624
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 13 genes
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Show members
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13 source identifiers mapped to 13 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
10682
10682
EBP
EBP cholestenol delta-isomerase [Source:HGNC ...
1595
1595
CYP51A1
cytochrome P450 family 51 subfamily A member ...
1717
1717
DHCR7
7-dehydrocholesterol reductase [Source:HGNC S...
1718
1718
DHCR24
24-dehydrocholesterol reductase [Source:HGNC ...
2222
2222
FDFT1
farnesyl-diphosphate farnesyltransferase 1 [S...
3930
3930
LBR
lamin B receptor [Source:HGNC Symbol;Acc:HGNC...
4047
4047
LSS
lanosterol synthase [Source:HGNC Symbol;Acc:H...
50814
50814
NSDHL
NAD(P) dependent steroid dehydrogenase-like [...
51478
51478
HSD17B7
hydroxysteroid 17-beta dehydrogenase 7 [Sourc...
6307
6307
MSMO1
methylsterol monooxygenase 1 [Source:HGNC Sym...
6309
6309
SC5D
sterol-C5-desaturase [Source:HGNC Symbol;Acc:...
6713
6713
SQLE
squalene epoxidase [Source:HGNC Symbol;Acc:HG...
7108
7108
TM7SF2
transmembrane 7 superfamily member 2 [Source:...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-143
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