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Human Gene Set: KEGG_MEDICUS_REFERENCE_BCR_PLCG_CALCINEURIN_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_REFERENCE_BCR_PLCG_CALCINEURIN_SIGNALING_PATHWAY
Systematic name
M47580
Brief description
Pathway Definition from KEGG: IGH -> (LYN,SYK) -> (BTK,BLNK) -> PLCG2 -> IP3 -> Ca2+ -> CALM == CN -> NFAT
Full description or abstract
BCR-PLCG-Calcineurin signaling pathway. Pathway ID: N00487. Pathway type: Reference. Pathway class: nt06220 Calcium signaling.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N00487
Related gene sets
External links
https://www.kegg.jp/entry/N00487
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
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Show members
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18 source identifiers mapped to 18 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
102723407
102723407
ENSG00000275063
novel transcript
29760
29760
BLNK
B cell linker [Source:HGNC Sy...
4067
4067
LYN
LYN proto-oncogene, Src famil...
4772
4772
NFATC1
nuclear factor of activated T...
4773
4773
NFATC2
nuclear factor of activated T...
4775
4775
NFATC3
nuclear factor of activated T...
4776
4776
NFATC4
nuclear factor of activated T...
5336
5336
PLCG2
phospholipase C gamma 2 [Sour...
5530
5530
PPP3CA
protein phosphatase 3 catalyt...
5532
5532
PPP3CB
protein phosphatase 3 catalyt...
5533
5533
PPP3CC
protein phosphatase 3 catalyt...
5534
5534
PPP3R1
protein phosphatase 3 regulat...
5535
5535
PPP3R2
protein phosphatase 3 regulat...
6850
6850
SYK
spleen associated tyrosine ki...
695
695
BTK
Bruton tyrosine kinase [Sourc...
801
801
CALM1
calmodulin 1 [Source:HGNC Sym...
805
805
CALM2
calmodulin 2 [Source:HGNC Sym...
808
808
CALM3
calmodulin 3 [Source:HGNC Sym...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-24
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