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Human Gene Set: KEGG_MEDICUS_REFERENCE_ATR_SIGNALING
Standard name
KEGG_MEDICUS_REFERENCE_ATR_SIGNALING
Systematic name
M47841
Brief description
Pathway Definition from KEGG: RPA == RAD17+9-1-1 == TOPBP1 == ATR+ATRIP -> CHEK1
Full description or abstract
ATR signaling. Pathway ID: N01451. Pathway type: Reference. Pathway class: nt06506 Double-strand break repair.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01451
Related gene sets
External links
https://www.kegg.jp/entry/N01451
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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json
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 12 genes
Gene families
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Show members
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12 source identifiers mapped to 12 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
11073
11073
TOPBP1
DNA topoisomerase II binding protein 1 [Source...
1111
1111
CHEK1
checkpoint kinase 1 [Source:HGNC Symbol;Acc:HG...
29935
29935
RPA4
replication protein A4 [Source:HGNC Symbol;Acc...
3364
3364
HUS1
HUS1 checkpoint clamp component [Source:HGNC S...
545
545
ATR
ATR serine/threonine kinase [Source:HGNC Symbo...
5810
5810
RAD1
RAD1 checkpoint DNA exonuclease [Source:HGNC S...
5883
5883
RAD9A
RAD9 checkpoint clamp component A [Source:HGNC...
5884
5884
RAD17
RAD17 checkpoint clamp loader component [Sourc...
6117
6117
RPA1
replication protein A1 [Source:HGNC Symbol;Acc...
6118
6118
RPA2
replication protein A2 [Source:HGNC Symbol;Acc...
6119
6119
RPA3
replication protein A3 [Source:HGNC Symbol;Acc...
84126
84126
ATRIP
ATR interacting protein [Source:HGNC Symbol;Ac...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-433
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