login
register
GSEA Home
Downloads
Molecular Signatures Database
Documentation
Contact
Team
MSigDB Home
Human Collections
About
Browse
Search
Investigate
Gene Families
Mouse Collections
About
Browse
Search
Investigate
Help
Human Gene Set: KEGG_MEDICUS_PATHOGEN_HIV_VPR_TO_CDC25_CELL_CYCLE_G2M
Standard name
KEGG_MEDICUS_PATHOGEN_HIV_VPR_TO_CDC25_CELL_CYCLE_G2M
Systematic name
M47573
Brief description
Pathway Definition from KEGG: Vpr == (DCAF1+DDB1+CUL4) -> ATR -> CHEK1 -| CDC25C -> (CCNB+CDK1)
Full description or abstract
HIV Vpr to CDC25-cell cycle G2M. Pathway ID: N00456. Pathway type: Pathogen. Pathway class: nt06161 Human immunodeficiency virus 1 (HIV-1).
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N00456
Related gene sets
External links
https://www.kegg.jp/entry/N00456
Filtered by similarity
?
Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
|
gmt
|
xml
|
json
|
TSV metadata
Compute overlaps
?
(
show
collections to investigate for overlap with this gene set)
H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
?
NG-CHM interactive heatmaps
(
Please note that clustering takes a few seconds
)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 11 genes
Gene families
?
Categorize
these 11 genes by gene family
Show members
(
show
11 source identifiers mapped to 11 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
1111
1111
CHEK1
checkpoint kinase 1 [Source:HGNC Symbol;Acc:HG...
1642
1642
DDB1
damage specific DNA binding protein 1 [Source:...
545
545
ATR
ATR serine/threonine kinase [Source:HGNC Symbo...
8450
8450
CUL4B
cullin 4B [Source:HGNC Symbol;Acc:HGNC:2555]
8451
8451
CUL4A
cullin 4A [Source:HGNC Symbol;Acc:HGNC:2554]
85417
85417
CCNB3
cyclin B3 [Source:HGNC Symbol;Acc:HGNC:18709]
891
891
CCNB1
cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579]
9133
9133
CCNB2
cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580]
9730
9730
DCAF1
DDB1 and CUL4 associated factor 1 [Source:HGNC...
983
983
CDK1
cyclin dependent kinase 1 [Source:HGNC Symbol;...
995
995
CDC25C
cell division cycle 25C [Source:HGNC Symbol;Ac...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-613
See
MSigDB license terms here
. Please note that certain gene sets have special access terms.