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Human Gene Set: KEGG_MEDICUS_ENV_FACTOR_METALS_TO_NFKB_SIGNALING_PATHWAY
Standard name
KEGG_MEDICUS_ENV_FACTOR_METALS_TO_NFKB_SIGNALING_PATHWAY
Systematic name
M47816
Brief description
Pathway Definition from KEGG: Metals -> ROS -| PTP -| SRC -> ABL -> PKD -> IKK -> NFKBIA -> NFKB
Full description or abstract
Metals to NFKB signaling pathway. Pathway ID: N01411. Pathway type: Env factor. Pathway class: nt06223 TNF signaling.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01411
Related gene sets
External links
https://www.kegg.jp/entry/N01411
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
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grp
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gmt
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xml
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
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these 15 genes
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Show members
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15 source identifiers mapped to 15 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
1147
1147
CHUK
component of inhibitor of nuclear factor kappa...
23683
23683
PRKD3
protein kinase D3 [Source:HGNC Symbol;Acc:HGNC...
25
25
ABL1
ABL proto-oncogene 1, non-receptor tyrosine ki...
25865
25865
PRKD2
protein kinase D2 [Source:HGNC Symbol;Acc:HGNC...
27
27
ABL2
ABL proto-oncogene 2, non-receptor tyrosine ki...
3551
3551
IKBKB
inhibitor of nuclear factor kappa B kinase sub...
4790
4790
NFKB1
nuclear factor kappa B subunit 1 [Source:HGNC ...
4792
4792
NFKBIA
NFKB inhibitor alpha [Source:HGNC Symbol;Acc:H...
52
52
ACP1
acid phosphatase 1 [Source:HGNC Symbol;Acc:HGN...
5587
5587
PRKD1
protein kinase D1 [Source:HGNC Symbol;Acc:HGNC...
5781
5781
PTPN11
protein tyrosine phosphatase non-receptor type...
5795
5795
PTPRJ
protein tyrosine phosphatase receptor type J [...
5970
5970
RELA
RELA proto-oncogene, NF-kB subunit [Source:HGN...
6714
6714
SRC
SRC proto-oncogene, non-receptor tyrosine kina...
8517
8517
IKBKG
inhibitor of nuclear factor kappa B kinase reg...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-352
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