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Human Gene Set: KEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY
Standard name
KEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY
Systematic name
M47817
Brief description
Pathway Definition from KEGG: Metals -> ROS -| KEAP1 -| NRF2 => (HMOX1,NQO1,AKR)
Full description or abstract
Metals to KEAP1-NRF2 signalig pathway. Pathway ID: N01413. Pathway type: Env factor. Pathway class: nt06226 KEAP1-NRF2 signaling.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01413
Related gene sets
External links
https://www.kegg.jp/entry/N01413
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
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gmt
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xml
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json
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 9 genes
Gene families
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these 9 genes by gene family
Show members
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show
9 source identifiers mapped to 9 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
10327
10327
AKR1A1
aldo-keto reductase family 1 member A1 [Source...
1109
1109
AKR1C4
aldo-keto reductase family 1 member C4 [Source...
1645
1645
AKR1C1
aldo-keto reductase family 1 member C1 [Source...
1646
1646
AKR1C2
aldo-keto reductase family 1 member C2 [Source...
1728
1728
NQO1
NAD(P)H quinone dehydrogenase 1 [Source:HGNC S...
3162
3162
HMOX1
heme oxygenase 1 [Source:HGNC Symbol;Acc:HGNC:...
4780
4780
NFE2L2
NFE2 like bZIP transcription factor 2 [Source:...
8644
8644
AKR1C3
aldo-keto reductase family 1 member C3 [Source...
9817
9817
KEAP1
kelch like ECH associated protein 1 [Source:HG...
Version history
2024.1.Hs: Updated to network file downloaded on 2024-05-614
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