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Human Gene Set: HP_REDUCED_NATURAL_KILLER_CELL_ACTIVITY
Standard name
HP_REDUCED_NATURAL_KILLER_CELL_ACTIVITY
Systematic name
M47205
Brief description
Reduced natural killer cell activity
Full description or abstract
Reduced ability of the natural killer cell to function in the adaptive immune response. [https://orcid.org/0000-0002-0736-9199]
Collection
C5: Ontology
HPO: Human Phenotype Ontology
Source publication
Exact source
HP:0012178
Related gene sets
External links
https://hpo.jax.org/app/browse/term/HP:0012178
Filtered by similarity
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1 similar ontology term(s) from the external resource)
External ID
External Name
HP:0012177
Abnormal natural killer cell physiology
Source species
Homo sapiens
Contributed by
Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 16 genes
Gene families
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these 16 genes by gene family
Show members
(
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16 source identifiers mapped to 16 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
201294
201294
UNC13D
unc-13 homolog D [Source:HGNC Symbol;Acc:HGN...
2214
2214
FCGR3A
Fc gamma receptor IIIa [Source:HGNC Symbol;A...
331
331
XIAP
X-linked inhibitor of apoptosis [Source:HGNC...
3561
3561
IL2RG
interleukin 2 receptor subunit gamma [Source...
3937
3937
LCP2
lymphocyte cytosolic protein 2 [Source:HGNC ...
4068
4068
SH2D1A
SH2 domain containing 1A [Source:HGNC Symbol...
5293
5293
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kina...
5551
5551
PRF1
perforin 1 [Source:HGNC Symbol;Acc:HGNC:9360]
5580
5580
PRKCD
protein kinase C delta [Source:HGNC Symbol;A...
58484
58484
NLRC4
NLR family CARD domain containing 4 [Source:...
6813
6813
STXBP2
syntaxin binding protein 2 [Source:HGNC Symb...
7454
7454
WAS
WASP actin nucleation promoting factor [Sour...
7456
7456
WIPF1
WAS/WASL interacting protein family member 1...
8517
8517
IKBKG
inhibitor of nuclear factor kappa B kinase r...
8546
8546
AP3B1
adaptor related protein complex 3 subunit be...
8676
8676
STX11
syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429]
Version history
2024.1.Hs: Updated to HPO Release 2024-04-26.
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