login
register
GSEA Home
Downloads
Molecular Signatures Database
Documentation
Contact
Team
MSigDB Home
Human Collections
About
Browse
Search
Investigate
Gene Families
Mouse Collections
About
Browse
Search
Investigate
Help
Human Gene Set: HP_INTERSTITIAL_CARDIAC_FIBROSIS
Standard name
HP_INTERSTITIAL_CARDIAC_FIBROSIS
Systematic name
M38456
Brief description
Interstitial cardiac fibrosis
Full description or abstract
A type of myocardial fibrosis characterized by excessive diffuse collagen accumulation concentrated in interstitial spaces. [PMID:10435025]
Collection
C5: Ontology
HPO: Human Phenotype Ontology
Source publication
Exact source
HP:0031329
Related gene sets
External links
https://hpo.jax.org/app/browse/term/HP:0031329
Filtered by similarity
?
Source species
Homo sapiens
Contributed by
Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
|
gmt
|
xml
|
json
|
TSV metadata
Compute overlaps
?
(
show
collections to investigate for overlap with this gene set)
H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
?
NG-CHM interactive heatmaps
(
Please note that clustering takes a few seconds
)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 10 genes
Gene families
?
Categorize
these 10 genes by gene family
Show members
(
show
10 source identifiers mapped to 10 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
10112
10112
KIF20A
kinesin family member 20A [Source:HGNC Symbol;...
22845
22845
DOLK
dolichol kinase [Source:HGNC Symbol;Acc:HGNC:2...
2318
2318
FLNC
filamin C [Source:HGNC Symbol;Acc:HGNC:3756]
4000
4000
LMNA
lamin A/C [Source:HGNC Symbol;Acc:HGNC:6636]
4625
4625
MYH7
myosin heavy chain 7 [Source:HGNC Symbol;Acc:H...
6123
6123
RPL3L
ribosomal protein L3 like [Source:HGNC Symbol;...
70
70
ACTC1
actin alpha cardiac muscle 1 [Source:HGNC Symb...
7137
7137
TNNI3
troponin I3, cardiac type [Source:HGNC Symbol;...
7139
7139
TNNT2
troponin T2, cardiac type [Source:HGNC Symbol;...
84665
84665
MYPN
myopalladin [Source:HGNC Symbol;Acc:HGNC:23246]
Version history
2024.1.Hs: Updated to HPO Release 2024-04-26.
See
MSigDB license terms here
. Please note that certain gene sets have special access terms.