login
register
GSEA Home
Downloads
Molecular Signatures Database
Documentation
Contact
Team
MSigDB Home
Human Collections
About
Browse
Search
Investigate
Gene Families
Mouse Collections
About
Browse
Search
Investigate
Help
Human Gene Set: HP_INCREASED_CIRCULATING_IRON_CONCENTRATION
Standard name
HP_INCREASED_CIRCULATING_IRON_CONCENTRATION
Systematic name
M36308
Brief description
Increased circulating iron concentration
Full description or abstract
The concentration of iron in the blood circulation is above the upper limit of normal. []
Collection
C5: Ontology
HPO: Human Phenotype Ontology
Source publication
Exact source
HP:0003452
Related gene sets
External links
https://hpo.jax.org/app/browse/term/HP:0003452
Filtered by similarity
?
Source species
Homo sapiens
Contributed by
Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
|
gmt
|
xml
|
json
|
TSV metadata
Compute overlaps
?
(
show
collections to investigate for overlap with this gene set)
H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
?
NG-CHM interactive heatmaps
(
Please note that clustering takes a few seconds
)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 13 genes
Gene families
?
Categorize
these 13 genes by gene family
Show members
(
show
13 source identifiers mapped to 13 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
148738
148738
HJV
hemojuvelin BMP co-receptor [Source:HGNC Sy...
2495
2495
FTH1
ferritin heavy chain 1 [Source:HGNC Symbol;...
29127
29127
RACGAP1
Rac GTPase activating protein 1 [Source:HGN...
3077
3077
HFE
homeostatic iron regulator [Source:HGNC Sym...
4891
4891
SLC11A2
solute carrier family 11 member 2 [Source:H...
5313
5313
PKLR
pyruvate kinase L/R [Source:HGNC Symbol;Acc...
55240
55240
STEAP3
STEAP3 metalloreductase [Source:HGNC Symbol...
57817
57817
HAMP
hepcidin antimicrobial peptide [Source:HGNC...
617
617
BCS1L
BCS1 homolog, ubiquinol-cytochrome c reduct...
650
650
BMP2
bone morphogenetic protein 2 [Source:HGNC S...
7036
7036
TFR2
transferrin receptor 2 [Source:HGNC Symbol;...
9493
9493
KIF23
kinesin family member 23 [Source:HGNC Symbo...
9652
9652
SKIC3
SKI3 subunit of superkiller complex [Source...
Version history
2024.1.Hs: Renamed from HP_INCREASED_SERUM_IRON. Updated to HPO Release 2024-04-26.
See
MSigDB license terms here
. Please note that certain gene sets have special access terms.