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Human Gene Set: HP_FOAM_CELLS
Standard name
HP_FOAM_CELLS
Systematic name
M36365
Brief description
Foam cells
Full description or abstract
The presence of foam cells, a type of macrophage that localizes to fatty deposits on blood vessel walls, where they ingest low-density lipoproteins and become laden with lipids, giving them a foamy appearance. [https://orcid.org/0000-0002-0736-9199]
Collection
C5: Ontology
HPO: Human Phenotype Ontology
Source publication
Exact source
HP:0003651
Related gene sets
External links
https://hpo.jax.org/app/browse/term/HP:0003651
Filtered by similarity
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Source species
Homo sapiens
Contributed by
Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
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grp
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 14 genes
Gene families
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these 14 genes by gene family
Show members
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show
14 source identifiers mapped to 14 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
10577
10577
NPC2
NPC intracellular cholesterol transporter 2 ...
1438
1438
CSF2RA
colony stimulating factor 2 receptor subunit...
1439
1439
CSF2RB
colony stimulating factor 2 receptor subunit...
2720
2720
GLB1
galactosidase beta 1 [Source:HGNC Symbol;Acc...
3123
3123
HLA-DRB1
major histocompatibility complex, class II, ...
348
348
APOE
apolipoprotein E [Source:HGNC Symbol;Acc:HGN...
3931
3931
LCAT
lecithin-cholesterol acyltransferase [Source...
3988
3988
LIPA
lipase A, lysosomal acid type [Source:HGNC S...
427
427
ASAH1
N-acylsphingosine amidohydrolase 1 [Source:H...
4758
4758
NEU1
neuraminidase 1 [Source:HGNC Symbol;Acc:HGNC...
4864
4864
NPC1
NPC intracellular cholesterol transporter 1 ...
5294
5294
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kina...
6309
6309
SC5D
sterol-C5-desaturase [Source:HGNC Symbol;Acc...
6609
6609
SMPD1
sphingomyelin phosphodiesterase 1 [Source:HG...
Version history
2024.1.Hs: Updated to HPO Release 2024-04-26.
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