Human Gene Set: HP_DYSREGULATED_NEGATIVE_EMOTIONAL_STATE


Standard name HP_DYSREGULATED_NEGATIVE_EMOTIONAL_STATE
Systematic name M50026
Brief description Dysregulated negative emotional state
Full description or abstract An emotional state characterized by excessive, persistent, or contextually inappropriate negative inner experiences involving emotional arousal and valence. These experiences are often associated with negative perceptions of the self, the future, the past, or the surrounding environment, and may include affective bias such as interpreting neutral or ambiguous stimuli as negative. The intensity, duration, or impact of the state exceeds what would be expected for the individual based on their baseline emotional functioning, the context, cultural norms, or situational triggers, or when it persists despite efforts at self-regulation. [PMID:27732016, PMID:36104987]
Collection C5: Ontology
      HPO: Human Phenotype Ontology
Source publication  
Exact source HP:0031467
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External links https://hpo.jax.org/app/browse/term/HP:0031467
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Source species Homo sapiens
Contributed by Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
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Version history 2026.1.Hs: Renamed from HP_ABNORMAL_NEGATIVE_EMOTIONAL_STATE. Updated to HPO Release 2026-01-08.


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