Human Gene Set: HP_DECREASED_CIRCULATING_TERMINAL_COMPLEMENT_COMPONENT_CONCENTRATION

Standard name

HP_DECREASED_CIRCULATING_TERMINAL_COMPLEMENT_COMPONENT_CONCENTRATION

Systematic name

M41572

Brief description

Decreased circulating terminal complement component concentration

Full description or abstract

Concentration below the lower limit of normal of one or more components of the the terminal membrane attack complex (MAC) portion of complement, which represents the lytic, pore-forming part of the system. The MAC comprises seven components: C5b, C6, C7, C8 (a heterotrimer composed of C8alpha, C8beta and C8gamma) and multiple copies of C9. [PMID:26841934]

Collection

C5: Ontology
HPO: Human Phenotype Ontology

Source publication

Exact source

HP:0033057

Related gene sets

External links

https://hpo.jax.org/app/browse/term/HP:0033057

Filtered by similarity ?

Source species

Homo sapiens

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