Human Gene Set: HP_ABNORMAL_SYNOVIAL_MEMBRANE_MORPHOLOGY
Standard name
HP_ABNORMAL_SYNOVIAL_MEMBRANE_MORPHOLOGY
Systematic name
M36673
Brief description
Abnormal synovial membrane morphology
Full description or abstract
Any structural anomaly of the synovium, which is a membrane that lines the cavity of synovial joints and consists of a lining layer of macrophage-like synoviocytes and fibroblast-like synoviocytes, as well as a sublining of connective tissue. Synovial cells are thought to contribute to joint homeostasis by secreting various factors such as hyaluronic acid and lubricin important for joint lubrication and function, as well as disposing of the waste products. [PMID:27412524]