Human Gene Set: HOLLEMAN_PREDNISOLONE_RESISTANCE_ALL_DN
Standard name
HOLLEMAN_PREDNISOLONE_RESISTANCE_ALL_DN
Systematic name
M2560
Brief description
Genes distinguishing prednisolone [PubChem=5755] resistant and sensitive ALL (B- and T-lineage ALL); here - genes down-regulated in the drug resistant samples.
Full description or abstract
Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percent of patients. However, the cause of treatment failure in the remaining 20 percent of patients is largely unknown.
Collection
C2: Curated CGP: Chemical and Genetic Perturbations
