Human Gene Set: HARRIS_HYPOXIA


Standard name HARRIS_HYPOXIA
Systematic name M10508
Brief description Genes known to be induced by hypoxia
Full description or abstract Cells undergo a variety of biological responses when placed in hypoxic conditions, including activation of signalling pathways that regulate proliferation, angiogenesis and death. Cancer cells have adapted these pathways, allowing tumours to survive and even grow under hypoxic conditions, and tumour hypoxia is associated with poor prognosis and resistance to radiation therapy. Many elements of the hypoxia-response pathway are therefore good candidates for therapeutic targeting.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 11902584   Authors: Harris AL
Exact source Box 1
Related gene sets (show 4 gene sets from the same authors)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by John Newman (University of Washington)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 81 genes
Gene families ? Categorize these 81 genes by gene family
Show members (show 81 source identifiers mapped to 81 genes)
Version history 3.0: Renamed from HYPOXIA_REVIEW

See MSigDB license terms here. Please note that certain gene sets have special access terms.