Human Gene Set: GSE9239_CTRL_VS_TNF_INHIBITOR_TREATED_DC_DN


Standard name GSE9239_CTRL_VS_TNF_INHIBITOR_TREATED_DC_DN
Systematic name M6966
Brief description Genes down-regulated in monocyte-derived dendritic cells: control versus TNF [GeneID=7124] inhibitor etanercept.
Full description or abstract The process for making monocyte derived DCs (moDCs) has been previously described (46). All analysis was performed on ?day 5? immature DCs. Etanercept 10mg/mL was added to experimental wells on days 0, 2, and 4. We chose this concentration of etanercept as it approximates the plasma concentration of drug when given 50mg BIW.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 18039949   Authors: Zaba LC,Cardinale I,Gilleaudeau P,Sullivan-Whalen M,Suárez-Fariñas M,Fuentes-Duculan J,Novitskaya I,Khatcherian A,Bluth MJ,Lowes MA,Krueger JG
Exact source GSE9239_2477_200_DN
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Source species Homo sapiens
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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identifier namespace		 HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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