Human Gene Set: GSE5099_MONOCYTE_VS_CLASSICAL_M1_MACROPHAGE_DN


Standard name GSE5099_MONOCYTE_VS_CLASSICAL_M1_MACROPHAGE_DN
Systematic name M6587
Brief description Genes down-regulated in monocytes versus classically activated (M1) macrophages.
Full description or abstract Monocytes mature tom acrophages in the presence of the lineage determining cytokine M-CSF. They can be further polarized into M1 or M2 macrophages with distinct functional properties. We used microarrays to detail the global programme of gene expression underlying macrophage maturation and polarization and identified distinct classes of up-regulated genes during this process.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 17082649   Authors: Martinez FO,Gordon S,Locati M,Mantovani A
Exact source GSE5099_3805_200_DN
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Source species Homo sapiens
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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identifier namespace		 HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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