Human Gene Set: GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_UP
Standard name
GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_UP
Systematic name
M6588
Brief description
Genes up-regulated in monocytes versus alternatively activated (M2) macrophages.
Full description or abstract
Monocytes mature tom acrophages in the presence of the lineage determining cytokine M-CSF. They can be further polarized into M1 or M2 macrophages with distinct functional properties. We used microarrays to detail the global programme of gene expression underlying macrophage maturation and polarization and identified distinct classes of up-regulated genes during this process.
