Human Gene Set: GSE3982_MAC_VS_CENT_MEMORY_CD4_TCELL_DN
Standard name
GSE3982_MAC_VS_CENT_MEMORY_CD4_TCELL_DN
Systematic name
M5507
Brief description
Genes down-regulated in comparison of macrophages versus central memory CD4 [GeneID=920] T cells.
Full description or abstract
In the present study we used Affymetrix oligonucleotide microarrays to produce gene transcription profiles for the major leukocyte types in humans. This comprehensive dataset enabled us to not only establish which genes were expressed in each leukocyte type, but also which genes were expressed in each subset after activation. The used of a comprehensive dataset of gene profiles from all the major human leukocyte subsets enabled a novel and powerful means for identification of genes associated with single leukocyte subsets, or different immune paradigms.