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Human Gene Set: GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_DN
Standard name
GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_DN
Systematic name
M8861
Brief description
Genes down-regulated in lymphoid primed multipotent progenitors versus granulocyte-monocyte progenitors.
Full description or abstract
Expression profiling of Rag2-deficient Ets1++ and Rag2-deficient Ets1-- mature NK cells and WT bone marrow progenitors, WT T cells, and WT Pro B cells
Collection
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
Source publication
Pubmed 22608498
Authors: Ramirez K,Chandler KJ,Spaulding C,Zandi S,Sigvardsson M,Graves BJ,Kee BL
Exact source
GSE37301_2608_200_DN
Related gene sets
(
show
57 additional gene sets from the source publication)
GSE37301_CD4_TCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN
GSE37301_CD4_TCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP
GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_DN
GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_UP
GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_CD4_TCELL_DN
GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_CD4_TCELL_UP
GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN
GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_GRAN_MONO_PROGENITOR_UP
GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_PRO_BCELL_DN
GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_PRO_BCELL_UP
GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_RAG2_KO_NK_CELL_DN
GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_RAG2_KO_NK_CELL_UP
GSE37301_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_RAG2_KO_NK_CELL_DN
GSE37301_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_RAG2_KO_NK_CELL_UP
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_DN
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_UP
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_COMMON_LYMPHOID_PROGENITOR_DN
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_COMMON_LYMPHOID_PROGENITOR_UP
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_GRAN_MONO_PROGENITOR_DN
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_GRAN_MONO_PROGENITOR_UP
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_DN
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_UP
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_MULTIPOTENT_PROGENITOR_DN
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_MULTIPOTENT_PROGENITOR_UP
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_PRO_BCELL_DN
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_PRO_BCELL_UP
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_DN
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_UP
GSE37301_LYMPHOID_PRIMED_MPP_VS_CD4_TCELL_DN
GSE37301_LYMPHOID_PRIMED_MPP_VS_CD4_TCELL_UP
GSE37301_LYMPHOID_PRIMED_MPP_VS_COMMON_LYMPHOID_PROGENITOR_DN
GSE37301_LYMPHOID_PRIMED_MPP_VS_COMMON_LYMPHOID_PROGENITOR_UP
GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_UP
GSE37301_LYMPHOID_PRIMED_MPP_VS_PRO_BCELL_DN
GSE37301_LYMPHOID_PRIMED_MPP_VS_PRO_BCELL_UP
GSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_DN
GSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_UP
GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_DN
GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_UP
GSE37301_MULTIPOTENT_PROGENITOR_VS_COMMON_LYMPHOID_PROGENITOR_DN
GSE37301_MULTIPOTENT_PROGENITOR_VS_COMMON_LYMPHOID_PROGENITOR_UP
GSE37301_MULTIPOTENT_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN
GSE37301_MULTIPOTENT_PROGENITOR_VS_GRAN_MONO_PROGENITOR_UP
GSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_DN
GSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_UP
GSE37301_MULTIPOTENT_PROGENITOR_VS_PRO_BCELL_DN
GSE37301_MULTIPOTENT_PROGENITOR_VS_PRO_BCELL_UP
GSE37301_MULTIPOTENT_PROGENITOR_VS_RAG2_KO_NK_CELL_DN
GSE37301_MULTIPOTENT_PROGENITOR_VS_RAG2_KO_NK_CELL_UP
GSE37301_PRO_BCELL_VS_CD4_TCELL_DN
GSE37301_PRO_BCELL_VS_CD4_TCELL_UP
GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN
GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP
GSE37301_PRO_BCELL_VS_RAG2_KO_NK_CELL_DN
GSE37301_PRO_BCELL_VS_RAG2_KO_NK_CELL_UP
GSE37301_RAG2_KO_VS_RAG2_AND_ETS1_KO_NK_CELL_DN
GSE37301_RAG2_KO_VS_RAG2_AND_ETS1_KO_NK_CELL_UP
(
show
2 gene sets from the same authors)
VILIMAS_NOTCH1_TARGETS_DN
VILIMAS_NOTCH1_TARGETS_UP
External links
Filtered by similarity
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Source species
Mus musculus
Contributed by
Jernej Godec (Dana-Farber Cancer Institute)
Source platform or
identifier namespace
HUMAN_GENE_SYMBOL
Dataset references
(
show
1 datasets)
GSE37301
Download gene set
format:
grp
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xml
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TSV metadata
Compute overlaps
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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Please note that clustering takes a few seconds
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
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Categorize
these 199 genes by gene family
Show members
(
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200 source identifiers mapped to 199 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
ABCC10
89845
ABCC10
ATP binding cassette subf...
ABI2
10152
ABI2
abl interactor 2 [Source:...
ACOT8
10005
ACOT8
acyl-CoA thioesterase 8 [...
ACYP2
98
ACYP2
acylphosphatase 2 [Source...
ADIPOR2
79602
ADIPOR2
adiponectin receptor 2 [S...
AKT1
207
AKT1
AKT serine/threonine kina...
ALOX5AP
241
ALOX5AP
arachidonate 5-lipoxygena...
AMDHD2
51005
AMDHD2
amidohydrolase domain con...
ANKRD36B
57730
ANKRD36B
ankyrin repeat domain 36B...
ANKZF1
55139
ANKZF1
ankyrin repeat and zinc f...
AP2A2
161
AP2A2
adaptor related protein c...
AP3S1
1176
AP3S1
adaptor related protein c...
ARAP3
64411
ARAP3
ArfGAP with RhoGAP domain...
ARL2
402
ARL2
ADP ribosylation factor l...
ARPC3
10094
ARPC3
actin related protein 2/3...
ARPC5
10092
ARPC5
actin related protein 2/3...
ASPSCR1
79058
ASPSCR1
ASPSCR1 tether for SLC2A4...
ASTE1
28990
ASTE1
asteroid homolog 1 [Sourc...
ATAD5
79915
ATAD5
ATPase family AAA domain ...
ATP2A3
489
ATP2A3
ATPase sarcoplasmic/endop...
ATPIF1
93974
ATP5IF1
ATP synthase inhibitory f...
BFAR
51283
BFAR
bifunctional apoptosis re...
C11orf2
738
VPS51
VPS51 subunit of GARP com...
C11orf48
79081
LBHD1
LBH domain containing 1 [...
C11orf61
79684
MSANTD2
Myb/SANT DNA binding doma...
C11orf67
28971
AAMDC
adipogenesis associated M...
C19orf66
55337
SHFL
shiftless antiviral inhib...
C1orf123
54987
CZIB
CXXC motif containing zin...
C2CD2
25966
C2CD2
C2 calcium dependent doma...
C6orf130
221443
OARD1
O-acyl-ADP-ribose deacyla...
CASP8AP2
9994
CASP8AP2
caspase 8 associated prot...
CASP9
842
CASP9
caspase 9 [Source:HGNC Sy...
CCDC92
80212
CCDC92
coiled-coil domain contai...
CD101
9398
CD101
CD101 molecule [Source:HG...
CDC7
8317
CDC7
cell division cycle 7 [So...
CDK19
23097
CDK19
cyclin dependent kinase 1...
CEACAM1
634
CEACAM1
CEA cell adhesion molecul...
CEP68
23177
CEP68
centrosomal protein 68 [S...
CHAF1A
10036
CHAF1A
chromatin assembly factor...
CHEK1
1111
CHEK1
checkpoint kinase 1 [Sour...
CKLF
51192
CKLF
chemokine like factor [So...
CSNK1G2
1455
CSNK1G2
casein kinase 1 gamma 2 [...
CTCF
10664
CTCF
CCCTC-binding factor [Sou...
CUL2
8453
CUL2
cullin 2 [Source:HGNC Sym...
DENND2D
79961
DENND2D
DENN domain containing 2D...
DHCR24
1718
DHCR24
24-dehydrocholesterol red...
DKFZP586I1420
DLGAP5
9787
DLGAP5
DLG associated protein 5 ...
DNMT1
1786
DNMT1
DNA methyltransferase 1 [...
DPP8
54878
DPP8
dipeptidyl peptidase 8 [S...
DYSF
8291
DYSF
dysferlin [Source:HGNC Sy...
E2F1
1869
E2F1
E2F transcription factor ...
E2F3
1871
E2F3
E2F transcription factor ...
EFCAB11
90141
EFCAB11
EF-hand calcium binding d...
EPB49
2039
DMTN
dematin actin binding pro...
ERCC3
2071
ERCC3
ERCC excision repair 3, T...
ERP29
10961
ERP29
endoplasmic reticulum pro...
ETV4
2118
ETV4
ETS variant transcription...
EXOC1
55763
EXOC1
exocyst complex component...
FAH
2184
FAH
fumarylacetoacetate hydro...
FAIM
55179
FAIM
Fas apoptotic inhibitory ...
FAM108A1
81926
ABHD17A
abhydrolase domain contai...
FAM65A
79567
RIPOR1
RHO family interacting ce...
FAM89B
23625
FAM89B
family with sequence simi...
FBXL4
26235
FBXL4
F-box and leucine rich re...
FEZ2
9637
FEZ2
fasciculation and elongat...
FGGY
55277
FGGY
FGGY carbohydrate kinase ...
FKBP2
2286
FKBP2
FKBP prolyl isomerase 2 [...
FLOT1
10211
FLOT1
flotillin 1 [Source:HGNC ...
FRAT1
10023
FRAT1
FRAT regulator of WNT sig...
GAS2L1
10634
GAS2L1
growth arrest specific 2 ...
GLB1
2720
GLB1
galactosidase beta 1 [Sou...
GLYR1
84656
GLYR1
glyoxylate reductase 1 ho...
GNAI2
2771
GNAI2
G protein subunit alpha i...
GPAA1
8733
GPAA1
glycosylphosphatidylinosi...
HAUS5
23354
HAUS5
HAUS augmin like complex ...
HERC2
8924
HERC2
HECT and RLD domain conta...
HINT1
3094
HINT1
histidine triad nucleotid...
HOXD13
3239
HOXD13
homeobox D13 [Source:HGNC...
HPS1
3257
HPS1
HPS1 biogenesis of lysoso...
HPS6
79803
HPS6
HPS6 biogenesis of lysoso...
HSD17B7
51478
HSD17B7
hydroxysteroid 17-beta de...
HSPB11
51668
IFT25
intraflagellar transport ...
IGKV3-20
28912
IGKV3-20
immunoglobulin kappa vari...
IL2RG
3561
IL2RG
interleukin 2 receptor su...
INPP4A
3631
INPP4A
inositol polyphosphate-4-...
INPP5A
3632
INPP5A
inositol polyphosphate-5-...
INPP5E
56623
INPP5E
inositol polyphosphate-5-...
INTS3
65123
INTS3
integrator complex subuni...
KCTD5
54442
KCTD5
potassium channel tetrame...
KDM5A
5927
KDM5A
lysine demethylase 5A [So...
KIAA0226
9711
RUBCN
rubicon autophagy regulat...
KIAA0430
9665
MARF1
meiosis regulator and mRN...
KIFAP3
22920
KIFAP3
kinesin associated protei...
LAMTOR2
28956
LAMTOR2
late endosomal/lysosomal ...
LEPROTL1
23484
LEPROTL1
leptin receptor overlappi...
LGALS3BP
3959
LGALS3BP
galectin 3 binding protei...
LOC100294145
100294145
ENSG00000289047
novel transcript
LPIN2
9663
LPIN2
lipin 2 [Source:HGNC Symb...
LY6E
4061
LY6E
lymphocyte antigen 6 fami...
MAN2B1
4125
MAN2B1
mannosidase alpha class 2...
MDC1
9656
MDC1
mediator of DNA damage ch...
MED16
10025
MED16
mediator complex subunit ...
MKRN1
23608
MKRN1
makorin ring finger prote...
MPHOSPH9
10198
MPHOSPH9
M-phase phosphoprotein 9 ...
MRFAP1L1
114932
MRFAP1L1
Morf4 family associated p...
MRPL34
64981
MRPL34
mitochondrial ribosomal p...
MTCP1NB
100272147
CMC4
C-X9-C motif containing 4...
MTMR1
8776
MTMR1
myotubularin related prot...
MX2
4600
MX2
MX dynamin like GTPase 2 ...
MYBL1
4603
MYBL1
MYB proto-oncogene like 1...
MYST2
11143
KAT7
lysine acetyltransferase ...
NCAM1
4684
NCAM1
neural cell adhesion mole...
NDUFS1
4719
NDUFS1
NADH:ubiquinone oxidoredu...
NOTCH2
4853
NOTCH2
notch receptor 2 [Source:...
NUP50
10762
NUP50
nucleoporin 50 [Source:HG...
NXT2
55916
NXT2
nuclear transport factor ...
OAS1
4938
OAS1
2'-5'-oligoadenylate synt...
OSTM1
28962
OSTM1
osteoclastogenesis associ...
PAFAH1B3
5050
PAFAH1B3
platelet activating facto...
PAQR4
124222
PAQR4
progestin and adipoQ rece...
PARP4
143
PARP4
poly(ADP-ribose) polymera...
PBLD
64081
PBLD
phenazine biosynthesis li...
PCMTD2
55251
PCMTD2
protein-L-isoaspartate (D...
PDGFD
80310
PDGFD
platelet derived growth f...
PHC1
1911
PHC1
polyhomeotic homolog 1 [S...
PHF20
51230
PHF20
PHD finger protein 20 [So...
PHTF2
57157
PHTF2
putative homeodomain tran...
PIGG
54872
PIGG
phosphatidylinositol glyc...
PIGN
23556
PIGN
phosphatidylinositol glyc...
PLA2G16
11145
PLAAT3
phospholipase A and acylt...
PPM1D
8493
PPM1D
protein phosphatase, Mg2+...
PPP2R5A
5525
PPP2R5A
protein phosphatase 2 reg...
PPT1
5538
PPT1
palmitoyl-protein thioest...
PRG2
5553
PRG2
proteoglycan 2, pro eosin...
PRKCI
5584
PRKCI
protein kinase C iota [So...
PXMP2
5827
PXMP2
peroxisomal membrane prot...
QRICH1
54870
QRICH1
glutamine rich 1 [Source:...
RABGAP1
23637
RABGAP1
RAB GTPase activating pro...
RANBP6
26953
RANBP6
RAN binding protein 6 [So...
RAP1GDS1
5910
RAP1GDS1
Rap1 GTPase-GDP dissociat...
RASSF1
11186
RASSF1
Ras association domain fa...
RMI1
80010
RMI1
RecQ mediated genome inst...
RNF170
81790
RNF170
ring finger protein 170 [...
ROCK1
6093
ROCK1
Rho associated coiled-coi...
RUSC1
23623
RUSC1
RUN and SH3 domain contai...
RWDD3
25950
RWDD3
RWD domain containing 3 [...
SC5DL
6309
SC5D
sterol-C5-desaturase [Sou...
SCCPDH
51097
SCCPDH
saccharopine dehydrogenas...
SEPHS2
22928
SEPHS2
selenophosphate synthetas...
SEPT9
10801
SEPTIN9
septin 9 [Source:HGNC Sym...
SH3BP1
23616
SH3BP1
SH3 domain binding protei...
SH3GL1
6455
SH3GL1
SH3 domain containing GRB...
SLC33A1
9197
SLC33A1
solute carrier family 33 ...
SLFN12
55106
SLFN12
schlafen family member 12...
SNAPC3
6619
SNAPC3
small nuclear RNA activat...
SNRK
54861
SNRK
SNF related kinase [Sourc...
SOCS2
8835
SOCS2
suppressor of cytokine si...
SOS1
6654
SOS1
SOS Ras/Rac guanine nucle...
SQRDL
58472
SQOR
sulfide quinone oxidoredu...
ST3GAL5
8869
ST3GAL5
ST3 beta-galactoside alph...
STAG1
10274
STAG1
STAG1 cohesin complex com...
STAP1
26228
STAP1
signal transducing adapto...
SUMO2
6613
SUMO2
small ubiquitin like modi...
TACC1
6867
TACC1
transforming acidic coile...
TCTA
6988
TCTA
T cell leukemia transloca...
TM7SF3
51768
TM7SF3
transmembrane 7 superfami...
TMEM168
64418
TMEM168
transmembrane protein 168...
TMEM41B
440026
TMEM41B
transmembrane protein 41B...
TMEM59
9528
TMEM59
transmembrane protein 59 ...
TMSB15B
286527
TMSB15B
thymosin beta 15B [Source...
TNFSF13
8741
TNFSF13
TNF superfamily member 13...
TNRC6B
23112
TNRC6B
trinucleotide repeat cont...
TOM1
10043
TOM1
target of myb1 membrane t...
TRIM26
7726
TRIM26
tripartite motif containi...
TRIM68
55128
TRIM68
tripartite motif containi...
TSPYL1
7259
TSPYL1
TSPY like 1 [Source:HGNC ...
TST
7263
TST
thiosulfate sulfurtransfe...
UBA3
9039
UBA3
ubiquitin like modifier a...
UBE2I
7329
UBE2I
ubiquitin conjugating enz...
USP20
10868
USP20
ubiquitin specific peptid...
USP21
27005
USP21
ubiquitin specific peptid...
VOPP1
81552
VOPP1
VOPP1 WW domain binding p...
WBSCR16
81554
RCC1L
RCC1 like [Source:HGNC Sy...
WDR37
22884
WDR37
WD repeat domain 37 [Sour...
WRB
7485
GET1
guided entry of tail-anch...
WWC3
55841
WWC3
WWC family member 3 [Sour...
WWOX
51741
WWOX
WW domain containing oxid...
WWP2
11060
WWP2
WW domain containing E3 u...
YAF2
10138
YAF2
YY1 associated factor 2 [...
YIPF1
54432
YIPF1
Yip1 domain family member...
ZBTB38
253461
ZBTB38
zinc finger and BTB domai...
ZDHHC3
51304
ZDHHC3
zinc finger DHHC-type pal...
ZFP64
55734
ZFP64
ZFP64 zinc finger protein...
ZMAT5
55954
ZMAT5
zinc finger matrin-type 5...
ZMIZ1
57178
ZMIZ1
zinc finger MIZ-type cont...
ZMYM6
9204
ZMYM6
zinc finger MYM-type cont...
ZNF217
7764
ZNF217
zinc finger protein 217 [...
ZNF518A
9849
ZNF518A
zinc finger protein 518A ...
ZNHIT1
10467
ZNHIT1
zinc finger HIT-type cont...
Version history
7.3: Moved to ImmuneSigDB sub-collection.
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