Human Gene Set: GSE34217_MIR17_92_OVEREXPRESS_VS_WT_ACT_CD8_TCELL_DN


Standard name GSE34217_MIR17_92_OVEREXPRESS_VS_WT_ACT_CD8_TCELL_DN
Systematic name M8915
Brief description Genes down-regulated in act CD8 T cells: over-expressing MIR17HG [GeneID=407975] versus activated control.
Full description or abstract During acute viral infections, effector CD8+ T cells differentiate into memory precursors or short-lived terminal effectors. miR-17-92a over-expression skews CD8+ effector cells to the terminal differentiation. We used microarray to identify the genes that are differentially expressed caused by miR-17-92a over-expression.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 22665768   Authors: Wu T,Wieland A,Araki K,Davis CW,Ye L,Hale JS,Ahmed R
Exact source GSE34217_3218_200_DN
Related gene sets (show 1 additional gene sets from the source publication)

(show 305 gene sets from the same authors)
External links
Filtered by similarity ?
Source species Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform or
identifier namespace
HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 137 genes
Gene families ? Categorize these 137 genes by gene family
Show members (show 200 source identifiers mapped to 137 genes)
Version history 7.3: Moved to ImmuneSigDB sub-collection.

See MSigDB license terms here. Please note that certain gene sets have special access terms.