Human Gene Set: GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_DN


Standard name GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_DN
Systematic name M8302
Brief description Genes down-regulated in peritoneal macrophages treated with LPS: wildtype versus KLF2 [GeneID=10365] knockout.
Full description or abstract Gene expression profile of LysMCre/Cre and KLF2?/? primary peritoneal macrophages following 6 hours of LPS treatment. We used microarrays to detail the global program of gene expression following LPS stimulation of LysMCre/Cre and KLF2?/? primary peritoneal macrophages. We identified distinct classes of genes that were altered following LPS stimulation.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 21565532   Authors: Mahabeleshwar GH,Kawanami D,Sharma N,Takami Y,Zhou G,Shi H,Nayak L,Jeyaraj D,Grealy R,White M,McManus R,Ryan T,Leahy P,Lin Z,Haldar SM,Atkins GB,Wong HR,Lingrel JB,Jain MK
Exact source GSE26727_2449_200_DN
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Source species Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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