Human Gene Set: GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_DN


Standard name GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_DN
Systematic name M8581
Brief description Genes down-regulated in Th17 cells 5 days post polarization: control versus stimulated with anti-CD3 and anti-CD28.
Full description or abstract Serial comparison between Th1 and Th17 tumor-specific cells cultured in vitro and ex vivo after transferred into sublethaly irradiated B6.PL mice. Th17-derived cells acquire Th1-like properties in vivo but maintain a distinct molecular profile.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 22177921   Authors: Muranski P,Borman ZA,Kerkar SP,Klebanoff CA,Ji Y,Sanchez-Perez L,Sukumar M,Reger RN,Yu Z,Kern SJ,Roychoudhuri R,Ferreyra GA,Shen W,Durum SK,Feigenbaum L,Palmer DC,Antony PA,Chan CC,Laurence A,Danner RL,Gattinoni L,Restifo NP
Exact source GSE26030_2564_200_DN
Related gene sets (show 15 additional gene sets from the source publication)

(show 102 gene sets from the same authors)
External links
Filtered by similarity ?
Source species Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 198 genes
Gene families ? Categorize these 198 genes by gene family
Show members (show 200 source identifiers mapped to 198 genes)
Version history 7.3: Moved to ImmuneSigDB sub-collection.

See MSigDB license terms here. Please note that certain gene sets have special access terms.