Human Gene Set: GSE25087_TREG_VS_TCONV_ADULT_DN


Standard name GSE25087_TREG_VS_TCONV_ADULT_DN
Systematic name M4652
Brief description Genes down-regulated in comparison of adult regulatory T cell (Treg) versus adult conventional T cells.
Full description or abstract We compared differences in fetal and adult T cells by performing whole genome profiling on sort-purified T cells (naïve CD4+ and Treg cells) from human fetal specimens (18-22 gestational weeks) and adult specimens (age 25-40 years old). Fetal and Adult Naïve CD4+ T cells phenotype: CD3+CD4+CD45RA+CCR7+CD27+, Fetal and Adult CD4+CD25+ Treg phenotype: CD3+CD4+CD25bright
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 21164017   Authors: Mold JE,Venkatasubrahmanyam S,Burt TD,Michaëlsson J,Rivera JM,Galkina SA,Weinberg K,Stoddart CA,McCune JM
Exact source GSE25087_1326_200_DN
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Source species Homo sapiens
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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identifier namespace		 HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.

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