Human Gene Set: GSE24814_STAT5_KO_VS_WT_PRE_BCELL_DN


Standard name GSE24814_STAT5_KO_VS_WT_PRE_BCELL_DN
Systematic name M8427
Brief description Genes down-regulated in pre-B cells: STAT5 knockout versus wildtype.
Full description or abstract In order to investigate the function of STAT5 in ALL, we isolated bone marrow cells from STAT5 fl/fl mice and transformed them with BCR-ABL1. In a second transduction the BCR-ABL1 driven pre-B cells were transformed either with CRE-GFP or empty vector control (GFP) and subjected to gene expression analysis.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 21911423   Authors: Hurtz C,Hatzi K,Cerchietti L,Braig M,Park E,Kim YM,Herzog S,Ramezani-Rad P,Jumaa H,Müller MC,Hofmann WK,Hochhaus A,Ye BH,Agarwal A,Druker BJ,Shah NP,Melnick AM,Müschen M
Exact source GSE24814_3047_200_DN
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Source species Mus musculus
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
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identifier namespace		 HUMAN_GENE_SYMBOL
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Version history 7.3: Moved to ImmuneSigDB sub-collection.


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