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Human Gene Set: GSE1925_CTRL_VS_3H_IFNG_STIM_MACROPHAGE_DN
Standard name
GSE1925_CTRL_VS_3H_IFNG_STIM_MACROPHAGE_DN
Systematic name
M6290
Brief description
Genes down-regulated in macrophages: untreated versus stimulated by IFNG
[GeneID=3458]
for 3h.
Full description or abstract
IFN-gamma transcriptional responses in control and IFN-gamma primed primary human macrophages
Collection
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
Source publication
Pubmed 16148108
Authors: Hu X,Park-Min KH,Ho HH,Ivashkiv LB
Exact source
GSE1925_3032_200_DN
Related gene sets
(
show
17 additional gene sets from the source publication)
GSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN
GSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP
GSE1925_3H_VS_24H_IFNG_STIM_MACROPHAGE_DN
GSE1925_3H_VS_24H_IFNG_STIM_MACROPHAGE_UP
GSE1925_CTRL_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN
GSE1925_CTRL_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP
GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_DN
GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_UP
GSE1925_CTRL_VS_3H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN
GSE1925_CTRL_VS_3H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP
GSE1925_CTRL_VS_3H_IFNG_STIM_MACROPHAGE_UP
GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_DN
GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_UP
GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_DN
GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_UP
GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_DN
GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_UP
(
show
36 gene sets from the same authors)
GSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_DN
GSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_UP
GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN
GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP
GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_DN
GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP
GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN
GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP
GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_DN
GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP
GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN
GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP
GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN
GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_UP
GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN
GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_UP
GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN
GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP
GSE11864_UNTREATED_VS_CSF1_IN_MAC_DN
GSE11864_UNTREATED_VS_CSF1_IN_MAC_UP
GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_DN
GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_UP
GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_DN
GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_UP
GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_WITH_IFNA_STIM_DN
GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_WITH_IFNA_STIM_UP
GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_DERIVED_MACROPHAGE_DN
GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_DERIVED_MACROPHAGE_UP
GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_IFNG_DERIVED_MACROPHAGE_DN
GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_IFNG_DERIVED_MACROPHAGE_UP
GSE37319_WT_VS_RC3H1_KO_CD44LOW_CD8_TCELL_DN
GSE37319_WT_VS_RC3H1_KO_CD44LOW_CD8_TCELL_UP
GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_DN
GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_UP
GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_DN
GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_UP
External links
Filtered by similarity
?
Source species
Homo sapiens
Contributed by
Jernej Godec (Dana-Farber Cancer Institute)
Source platform or
identifier namespace
HUMAN_GENE_SYMBOL
Dataset references
(
show
1 datasets)
GSE1925
Download gene set
format:
grp
|
gmt
|
xml
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json
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TSV metadata
Compute overlaps
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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Please note that clustering takes a few seconds
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 199 genes
Gene families
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Categorize
these 199 genes by gene family
Show members
(
show
200 source identifiers mapped to 199 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
ABHD5
51099
ABHD5
abhydrolase domain contain...
ACO1
48
ACO1
aconitase 1 [Source:HGNC S...
ADAM11
4185
ADAM11
ADAM metallopeptidase doma...
ADCY6
112
ADCY6
adenylate cyclase 6 [Sourc...
AGTR1
185
AGTR1
angiotensin II receptor ty...
AKR1A1
10327
AKR1A1
aldo-keto reductase family...
ANGPT4
51378
ANGPT4
angiopoietin 4 [Source:HGN...
ANXA3
306
ANXA3
annexin A3 [Source:HGNC Sy...
AQP1
358
AQP1
aquaporin 1 (Colton blood ...
AQP4
361
AQP4
aquaporin 4 [Source:HGNC S...
ARFIP2
23647
ARFIP2
ADP ribosylation factor in...
ARPP21
10777
ARPP21
cAMP regulated phosphoprot...
ASB4
51666
ASB4
ankyrin repeat and SOCS bo...
ATP4B
496
ATP4B
ATPase H+/K+ transporting ...
AURKAIP1
54998
AURKAIP1
aurora kinase A interactin...
BCCIP
56647
BCCIP
BRCA2 and CDKN1A interacti...
BCHE
590
BCHE
butyrylcholinesterase [Sou...
BCKDHB
594
BCKDHB
branched chain keto acid d...
BRAF
673
BRAF
B-Raf proto-oncogene, seri...
BV25S1J1.2
C11orf30
56946
EMSY
EMSY transcriptional repre...
C4BPB
725
C4BPB
complement component 4 bin...
C6orf10
10665
TSBP1
testis expressed basic pro...
CADPS
8618
CADPS
calcium dependent secretio...
CCDC88A
55704
CCDC88A
coiled-coil domain contain...
CCL23
6368
CCL23
C-C motif chemokine ligand...
CCNT1
904
CCNT1
cyclin T1 [Source:HGNC Sym...
CCR4
1233
CCR4
C-C motif chemokine recept...
CCT4
10575
CCT4
chaperonin containing TCP1...
CD177
57126
CD177
CD177 molecule [Source:HGN...
CD1C
911
CD1C
CD1c molecule [Source:HGNC...
CD24
100133941
CD24
CD24 molecule [Source:HGNC...
CD33
945
CD33
CD33 molecule [Source:HGNC...
CD80
941
CD80
CD80 molecule [Source:HGNC...
CDR1
1038
CDR1
cerebellar degeneration re...
CHST3
9469
CHST3
carbohydrate sulfotransfer...
CLIC2
1193
CLIC2
chloride intracellular cha...
CLMN
79789
CLMN
calmin [Source:HGNC Symbol...
COL19A1
1310
COL19A1
collagen type XIX alpha 1 ...
CPA3
1359
CPA3
carboxypeptidase A3 [Sourc...
CPB1
1360
CPB1
carboxypeptidase B1 [Sourc...
CRISP2
7180
CRISP2
cysteine rich secretory pr...
CST7
8530
CST7
cystatin F [Source:HGNC Sy...
CTAGE1
64693
CTAGE1
cutaneous T cell lymphoma-...
CTAGE11P
647288
CTAGE11P
CTAGE family member 11, ps...
CUX1
1523
CUX1
cut like homeobox 1 [Sourc...
CYP4F11
57834
CYP4F11
cytochrome P450 family 4 s...
CYP7B1
9420
CYP7B1
cytochrome P450 family 7 s...
DCAF17
80067
DCAF17
DDB1 and CUL4 associated f...
DCT
1638
DCT
dopachrome tautomerase [So...
DEFA4
1669
DEFA4
defensin alpha 4 [Source:H...
DEFB126
81623
DEFB126
defensin beta 126 [Source:...
DGKG
1608
DGKG
diacylglycerol kinase gamm...
DIABLO
56616
DIABLO
diablo IAP-binding mitocho...
DNAJA4
55466
DNAJA4
DnaJ heat shock protein fa...
DNAJC12
56521
DNAJC12
DnaJ heat shock protein fa...
DSTYK
25778
DSTYK
dual serine/threonine and ...
DUOX2
50506
DUOX2
dual oxidase 2 [Source:HGN...
DUSP1
1843
DUSP1
dual specificity phosphata...
ECM2
1842
ECM2
extracellular matrix prote...
EDA2R
60401
EDA2R
ectodysplasin A2 receptor ...
EFNA5
1946
EFNA5
ephrin A5 [Source:HGNC Sym...
EIF4G3
8672
EIF4G3
eukaryotic translation ini...
EPAS1
2034
EPAS1
endothelial PAS domain pro...
EPB41L4B
54566
EPB41L4B
erythrocyte membrane prote...
EPRS
2058
EPRS1
glutamyl-prolyl-tRNA synth...
FAM168B
130074
FAM168B
family with sequence simil...
FCGR1A
2209
FCGR1A
Fc gamma receptor Ia [Sour...
FGF20
26281
FGF20
fibroblast growth factor 2...
FRMD4B
23150
FRMD4B
FERM domain containing 4B ...
GABRB1
2560
GABRB1
gamma-aminobutyric acid ty...
GABRB2
2561
GABRB2
gamma-aminobutyric acid ty...
GARNL3
84253
GARNL3
GTPase activating Rap/RanG...
GLRA3
8001
GLRA3
glycine receptor alpha 3 [...
GOT1
2805
GOT1
glutamic-oxaloacetic trans...
GOT2
2806
GOT2
glutamic-oxaloacetic trans...
GP5
2814
GP5
glycoprotein V platelet [S...
GPR19
2842
GPR19
G protein-coupled receptor...
GPX5
2880
GPX5
glutathione peroxidase 5 [...
GRK4
2868
GRK4
G protein-coupled receptor...
HBBP1
3044
HBBP1
hemoglobin subunit beta ps...
HBQ1
3049
HBQ1
hemoglobin subunit theta 1...
HIP1
3092
HIP1
huntingtin interacting pro...
HIST1H3E
8353
H3C6
H3 clustered histone 6 [So...
HPR
3250
HPR
haptoglobin-related protei...
HS3ST3B1
9953
HS3ST3B1
heparan sulfate-glucosamin...
HSPA2
3306
HSPA2
heat shock protein family ...
HYAL4
23553
HYAL4
hyaluronidase 4 [Source:HG...
IFNA6
3443
IFNA6
interferon alpha 6 [Source...
IFNG
3458
IFNG
interferon gamma [Source:H...
IL18RAP
8807
IL18RAP
interleukin 18 receptor ac...
IL1RL1
9173
IL1RL1
interleukin 1 receptor lik...
IPO4
79711
IPO4
importin 4 [Source:HGNC Sy...
JUN
3725
JUN
Jun proto-oncogene, AP-1 t...
KCND2
3751
KCND2
potassium voltage-gated ch...
KCNJ15
3772
KCNJ15
potassium inwardly rectify...
KCNK12
56660
KCNK12
potassium two pore domain ...
KIF1B
23095
KIF1B
kinesin family member 1B [...
KIR2DS2
100132285
KIR2DS2
killer cell immunoglobulin...
KRT2
3849
KRT2
keratin 2 [Source:HGNC Sym...
LHX2
9355
LHX2
LIM homeobox 2 [Source:HGN...
LIPG
9388
LIPG
lipase G, endothelial type...
LOC100130331
100130331
ENSG00000237250
novel transcript
LOC730101
730101
ENSG00000291006
novel transcript
LPPR1
54886
PLPPR1
phospholipid phosphatase r...
LSM7
51690
LSM7
LSM7 homolog, U6 small nuc...
LTA4H
4048
LTA4H
leukotriene A4 hydrolase [...
LZTR1
8216
LZTR1
leucine zipper like post t...
MAGEA12
4111
MAGEA12
MAGE family member A12 [So...
MED8
112950
MED8
mediator complex subunit 8...
MFAP5
8076
MFAP5
microfibril associated pro...
MGLL
11343
MGLL
monoglyceride lipase [Sour...
MIF
4282
MIF
macrophage migration inhib...
MNDA
4332
MNDA
myeloid cell nuclear diffe...
MS4A6A
64231
MS4A6A
membrane spanning 4-domain...
MYOZ3
91977
MYOZ3
myozenin 3 [Source:HGNC Sy...
NACC2
138151
NACC2
NACC family member 2 [Sour...
NBLA00301
79804
HAND2-AS1
HAND2 antisense RNA 1 [Sou...
NECAB3
63941
NECAB3
N-terminal EF-hand calcium...
NET1
10276
NET1
neuroepithelial cell trans...
NLE1
54475
NLE1
notchless homolog 1 [Sourc...
NQO2
4835
NQO2
N-ribosyldihydronicotinami...
NUDT13
25961
NUDT13
nudix hydrolase 13 [Source...
NYNRIN
57523
NYNRIN
NYN domain and retroviral ...
OGFRL1
79627
OGFRL1
opioid growth factor recep...
OR2C1
4993
OR2C1
olfactory receptor family ...
PCDHB8
56128
PCDHB8
protocadherin beta 8 [Sour...
PEX2
5828
PEX2
peroxisomal biogenesis fac...
PIGR
5284
PIGR
polymeric immunoglobulin r...
PIM1
5292
PIM1
Pim-1 proto-oncogene, seri...
PLAT
5327
PLAT
plasminogen activator, tis...
PNPLA4
8228
PNPLA4
patatin like phospholipase...
POU3F2
5454
POU3F2
POU class 3 homeobox 2 [So...
PPL
5493
PPL
periplakin [Source:HGNC Sy...
PRAMEF12
390999
PRAMEF12
PRAME family member 12 [So...
PREB
10113
PREB
prolactin regulatory eleme...
PRO1768
29018
FOXN3-AS2
FOXN3 antisense RNA 2 [Sou...
PSG3
5671
PSG3
pregnancy specific beta-1-...
PTPN1
5770
PTPN1
protein tyrosine phosphata...
RABAC1
10567
RABAC1
Rab acceptor 1 [Source:HGN...
RALYL
138046
RALYL
RALY RNA binding protein l...
RGS17
26575
RGS17
regulator of G protein sig...
RIC3
79608
RIC3
RIC3 acetylcholine recepto...
RMND5B
64777
RMND5B
required for meiotic nucle...
RNF130
55819
RNF130
ring finger protein 130 [S...
RNF185
91445
RNF185
ring finger protein 185 [S...
RNF24
11237
RNF24
ring finger protein 24 [So...
RORB
6096
RORB
RAR related orphan recepto...
RPL13
6137
RPL13
ribosomal protein L13 [Sou...
RPL3
6122
RPL3
ribosomal protein L3 [Sour...
SCN10A
6336
SCN10A
sodium voltage-gated chann...
SCN9A
6335
SCN9A
sodium voltage-gated chann...
SERPINE2
5270
SERPINE2
serpin family E member 2 [...
SH3BP4
23677
SH3BP4
SH3 domain binding protein...
SHB
6461
SHB
SH2 domain containing adap...
SLC12A2
6558
SLC12A2
solute carrier family 12 m...
SLC19A3
80704
SLC19A3
solute carrier family 19 m...
SLC22A1
6580
SLC22A1
solute carrier family 22 m...
SLC25A3
5250
SLC25A3
solute carrier family 25 m...
SLC2A1
6513
SLC2A1
solute carrier family 2 me...
SLC34A1
6569
SLC34A1
solute carrier family 34 m...
SLC34A2
10568
SLC34A2
solute carrier family 34 m...
SLC37A4
2542
SLC37A4
solute carrier family 37 m...
SLC7A2
6542
SLC7A2
solute carrier family 7 me...
SLCO1A2
6579
SLCO1A2
solute carrier organic ani...
SPAM1
6677
SPAM1
sperm adhesion molecule 1 ...
SPARC
6678
SPARC
secreted protein acidic an...
SPIN1
10927
SPIN1
spindlin 1 [Source:HGNC Sy...
ST3GAL6
10402
ST3GAL6
ST3 beta-galactoside alpha...
STON1
11037
STON1
stonin 1 [Source:HGNC Symb...
STX12
23673
STX12
syntaxin 12 [Source:HGNC S...
SYT13
57586
SYT13
synaptotagmin 13 [Source:H...
TBC1D22A
25771
TBC1D22A
TBC1 domain family member ...
TDP1
55775
TDP1
tyrosyl-DNA phosphodiester...
TFF1
7031
TFF1
trefoil factor 1 [Source:H...
TMEM158
25907
TMEM158
transmembrane protein 158 ...
TMEM186
25880
TMEM186
transmembrane protein 186 ...
TMEM90B
79953
SYNDIG1
synapse differentiation in...
TMPRSS11D
9407
TMPRSS11D
transmembrane serine prote...
TNFRSF21
27242
TNFRSF21
TNF receptor superfamily m...
TPST2
8459
TPST2
tyrosylprotein sulfotransf...
TRAF3IP2
10758
TRAF3IP2
TRAF3 interacting protein ...
TRH
7200
TRH
thyrotropin releasing horm...
TTC30A
92104
IFT70A
intraflagellar transport 7...
TTR
7276
TTR
transthyretin [Source:HGNC...
TUBA1C
84790
TUBA1C
tubulin alpha 1c [Source:H...
TUFT1
7286
TUFT1
tuftelin 1 [Source:HGNC Sy...
UBE2NL
389898
UBE2NL
ubiquitin conjugating enzy...
UCP2
7351
UCP2
uncoupling protein 2 [Sour...
UROD
7389
UROD
uroporphyrinogen decarboxy...
VDAC2
7417
VDAC2
voltage dependent anion ch...
VNN1
8876
VNN1
vanin 1 [Source:HGNC Symbo...
VWF
7450
VWF
von Willebrand factor [Sou...
YIPF1
54432
YIPF1
Yip1 domain family member ...
ZBTB38
253461
ZBTB38
zinc finger and BTB domain...
ZCCHC4
29063
ZCCHC4
zinc finger CCHC-type cont...
ZDHHC8P1
150244
ZDHHC8BP
ZDHHC8B, pseudogene [Sourc...
ZNF197
10168
ZNF197
zinc finger protein 197 [S...
ZNF35
7584
ZNF35
zinc finger protein 35 [So...
ZNF43
7594
ZNF43
zinc finger protein 43 [So...
Version history
7.3: Moved to ImmuneSigDB sub-collection.
See
MSigDB license terms here
. Please note that certain gene sets have special access terms.