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Human Gene Set: GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_DN
Standard name
GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_DN
Systematic name
M6294
Brief description
Genes down-regulated in macrophages: untreated versus stimulated by IFNG
[GeneID=3458]
for 24h.
Full description or abstract
IFN-gamma transcriptional responses in control and IFN-gamma primed primary human macrophages
Collection
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
Source publication
Pubmed 16148108
Authors: Hu X,Park-Min KH,Ho HH,Ivashkiv LB
Exact source
GSE1925_3033_200_DN
Related gene sets
(
show
17 additional gene sets from the source publication)
GSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN
GSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP
GSE1925_3H_VS_24H_IFNG_STIM_MACROPHAGE_DN
GSE1925_3H_VS_24H_IFNG_STIM_MACROPHAGE_UP
GSE1925_CTRL_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN
GSE1925_CTRL_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP
GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_UP
GSE1925_CTRL_VS_3H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN
GSE1925_CTRL_VS_3H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP
GSE1925_CTRL_VS_3H_IFNG_STIM_MACROPHAGE_DN
GSE1925_CTRL_VS_3H_IFNG_STIM_MACROPHAGE_UP
GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_DN
GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_UP
GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_DN
GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_UP
GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_DN
GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_UP
(
show
36 gene sets from the same authors)
GSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_DN
GSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_UP
GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN
GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP
GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_DN
GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP
GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN
GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP
GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_DN
GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP
GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN
GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP
GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN
GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_UP
GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN
GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_UP
GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN
GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP
GSE11864_UNTREATED_VS_CSF1_IN_MAC_DN
GSE11864_UNTREATED_VS_CSF1_IN_MAC_UP
GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_DN
GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_UP
GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_DN
GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_UP
GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_WITH_IFNA_STIM_DN
GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_WITH_IFNA_STIM_UP
GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_DERIVED_MACROPHAGE_DN
GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_DERIVED_MACROPHAGE_UP
GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_IFNG_DERIVED_MACROPHAGE_DN
GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_IFNG_DERIVED_MACROPHAGE_UP
GSE37319_WT_VS_RC3H1_KO_CD44LOW_CD8_TCELL_DN
GSE37319_WT_VS_RC3H1_KO_CD44LOW_CD8_TCELL_UP
GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_DN
GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_UP
GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_DN
GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_UP
External links
Filtered by similarity
?
Source species
Homo sapiens
Contributed by
Jernej Godec (Dana-Farber Cancer Institute)
Source platform or
identifier namespace
HUMAN_GENE_SYMBOL
Dataset references
(
show
1 datasets)
GSE1925
Download gene set
format:
grp
|
gmt
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xml
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TSV metadata
Compute overlaps
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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NG-CHM interactive heatmaps
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
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Gene families
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Categorize
these 195 genes by gene family
Show members
(
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200 source identifiers mapped to 195 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
ABCC5
10057
ABCC5
ATP binding cassette subfa...
ABCE1
6059
ABCE1
ATP binding cassette subfa...
AHI1
54806
AHI1
Abelson helper integration...
AKIRIN1
79647
AKIRIN1
akirin 1 [Source:HGNC Symb...
ANKS1B
56899
ANKS1B
ankyrin repeat and sterile...
APCDD1L
164284
APCDD1L
APC down-regulated 1 like ...
AQP2
359
AQP2
aquaporin 2 [Source:HGNC S...
ARAP3
64411
ARAP3
ArfGAP with RhoGAP domain,...
ARHGAP9
64333
ARHGAP9
Rho GTPase activating prot...
ARL4A
10124
ARL4A
ADP ribosylation factor li...
ARMCX2
9823
ARMCX2
armadillo repeat containin...
ATP6V1G1
9550
ATP6V1G1
ATPase H+ transporting V1 ...
BAG3
9531
BAG3
BAG cochaperone 3 [Source:...
BAZ1B
9031
BAZ1B
bromodomain adjacent to zi...
BRF1
2972
BRF1
BRF1 RNA polymerase III tr...
C10orf71
118461
C10orf71
chromosome 10 open reading...
C11orf80
79703
TOP6BL
TOP6B like initiator of me...
C16orf42
115939
TSR3
TSR3 ribosome maturation f...
C16orf61
56942
CMC2
C-X9-C motif containing 2 ...
C19orf18
147685
C19orf18
chromosome 19 open reading...
C1QC
714
C1QC
complement C1q C chain [So...
C1QTNF4
114900
C1QTNF4
C1q and TNF related 4 [Sou...
C20orf20
55257
MRGBP
MRG domain binding protein...
C20orf29
55317
AP5S1
adaptor related protein co...
C2orf71
388939
PCARE
photoreceptor cilium actin...
C3orf37
56941
HMCES
5-hydroxymethylcytosine bi...
C5orf34
375444
C5orf34
chromosome 5 open reading ...
C5orf47
133491
C5orf47
chromosome 5 open reading ...
C5orf64
285668
C5orf64
chromosome 5 putative open...
CBFA2T2
9139
CBFA2T2
CBFA2/RUNX1 partner transc...
CCDC147
159686
CFAP58
cilia and flagella associa...
CCT2
10576
CCT2
chaperonin containing TCP1...
CD180
4064
CD180
CD180 molecule [Source:HGN...
CDC42BPA
8476
CDC42BPA
CDC42 binding protein kina...
CDC7
8317
CDC7
cell division cycle 7 [Sou...
CLDN7
1366
CLDN7
claudin 7 [Source:HGNC Sym...
CLRN1
7401
CLRN1
clarin 1 [Source:HGNC Symb...
CLUAP1
23059
CLUAP1
clusterin associated prote...
CNPY4
245812
CNPY4
canopy FGF signaling regul...
COL13A1
1305
COL13A1
collagen type XIII alpha 1...
CS
1431
CS
citrate synthase [Source:H...
CST8
10047
CST8
cystatin 8 [Source:HGNC Sy...
CYBB
1536
CYBB
cytochrome b-245 beta chai...
DCLRE1A
9937
DCLRE1A
DNA cross-link repair 1A [...
DCUN1D5
84259
DCUN1D5
defective in cullin neddyl...
DDX26B
203522
INTS6L
integrator complex subunit...
DENND1B
163486
DENND1B
DENN domain containing 1B ...
DNAJB5
25822
DNAJB5
DnaJ heat shock protein fa...
DRAP1
10589
DRAP1
DR1 associated protein 1 [...
DYNC1LI1
51143
DYNC1LI1
dynein cytoplasmic 1 light...
EBNA1BP2
10969
EBNA1BP2
EBNA1 binding protein 2 [S...
EEF1B2
1933
EEF1B2
eukaryotic translation elo...
EFR3B
22979
EFR3B
EFR3 homolog B [Source:HGN...
EIF3I
8668
EIF3I
eukaryotic translation ini...
EMR3
84658
ADGRE3
adhesion G protein-coupled...
ENG
2022
ENG
endoglin [Source:HGNC Symb...
ENTPD1
953
ENTPD1
ectonucleoside triphosphat...
ERI2
112479
ERI2
ERI1 exoribonuclease famil...
ESD
2098
ESD
esterase D [Source:HGNC Sy...
ETHE1
23474
ETHE1
ETHE1 persulfide dioxygena...
F13B
2165
F13B
coagulation factor XIII B ...
FAM129B
64855
NIBAN2
niban apoptosis regulator ...
FAM91A2
FANCC
2176
FANCC
FA complementation group C...
FGF11
2256
FGF11
fibroblast growth factor 1...
FKBP14
55033
FKBP14
FKBP prolyl isomerase 14 [...
FLJ30064
FTHL17
53940
FTHL17
ferritin heavy chain like ...
FTSJ1
24140
FTSJ1
FtsJ RNA 2'-O-methyltransf...
GNPNAT1
64841
GNPNAT1
glucosamine-phosphate N-ac...
GPR108
56927
GPR108
G protein-coupled receptor...
GPR172B
55065
SLC52A1
solute carrier family 52 m...
GSG1
83445
GSG1
germ cell associated 1 [So...
GSS
2937
GSS
glutathione synthetase [So...
GTPBP3
84705
GTPBP3
GTP binding protein 3, mit...
HIST1H4L
8368
H4C13
H4 clustered histone 13 [S...
IL1RN
3557
IL1RN
interleukin 1 receptor ant...
IL27RA
9466
IL27RA
interleukin 27 receptor su...
IL2RG
3561
IL2RG
interleukin 2 receptor sub...
INPPL1
3636
INPPL1
inositol polyphosphate pho...
IPO9
55705
IPO9
importin 9 [Source:HGNC Sy...
KANK1
23189
KANK1
KN motif and ankyrin repea...
KCNN4
3783
KCNN4
potassium calcium-activate...
KHK
3795
KHK
ketohexokinase [Source:HGN...
KIAA1486
57624
NYAP2
neuronal tyrosine-phosphor...
KIF1B
23095
KIF1B
kinesin family member 1B [...
KIRREL3
84623
KIRREL3
kirre like nephrin family ...
LOC100130642
LOC100130894
100130894
VAC14-AS1
VAC14 antisense RNA 1 [Sou...
LOC100134713
100134713
NDUFB2-AS1
NDUFB2 antisense RNA 1 [So...
LOC100287017
LOC400748
400748
ENSG00000235143
novel transcript
LOC440864
LOC643837
643837
LINC01128
long intergenic non-protei...
LPAR5
57121
LPAR5
lysophosphatidic acid rece...
LRRC25
126364
LRRC25
leucine rich repeat contai...
LTBP2
4053
LTBP2
latent transforming growth...
MAP7
9053
MAP7
microtubule associated pro...
MCM3AP-AS1
114044
MCM3AP-AS1
MCM3AP antisense RNA 1 [So...
METAP2
10988
METAP2
methionyl aminopeptidase 2...
MGRN1
23295
MGRN1
mahogunin ring finger 1 [S...
MINA
84864
RIOX2
ribosomal oxygenase 2 [Sou...
MMP8
4317
MMP8
matrix metallopeptidase 8 ...
MOBKL1A
92597
MOB1B
MOB kinase activator 1B [S...
MPP6
51678
PALS2
protein associated with LI...
MRPL24
79590
MRPL24
mitochondrial ribosomal pr...
MRPL50
54534
MRPL50
mitochondrial ribosomal pr...
MRPS5
64969
MRPS5
mitochondrial ribosomal pr...
MTX3
345778
MTX3
metaxin 3 [Source:HGNC Sym...
NAT15
79903
NAA60
N-alpha-acetyltransferase ...
NAV1
89796
NAV1
neuron navigator 1 [Source...
NCRNA00285
246312
C21orf91-OT1
C21orf91 overlapping trans...
NME1
4830
NME1
NME/NM23 nucleoside diphos...
NOD2
64127
NOD2
nucleotide binding oligome...
NRM
11270
NRM
nurim [Source:HGNC Symbol;...
NUDT4
11163
NUDT4
nudix hydrolase 4 [Source:...
OCLN
100506658
OCLN
occludin [Source:HGNC Symb...
ORMDL1
94101
ORMDL1
ORMDL sphingolipid biosynt...
PAICS
10606
PAICS
phosphoribosylaminoimidazo...
PANX1
24145
PANX1
pannexin 1 [Source:HGNC Sy...
PEBP4
157310
PEBP4
phosphatidylethanolamine b...
PFN1
5216
PFN1
profilin 1 [Source:HGNC Sy...
PHLDA2
7262
PHLDA2
pleckstrin homology like d...
PIGF
5281
PIGF
phosphatidylinositol glyca...
PLOD3
8985
PLOD3
procollagen-lysine,2-oxogl...
PLXND1
23129
PLXND1
plexin D1 [Source:HGNC Sym...
PNMT
5409
PNMT
phenylethanolamine N-methy...
PPP6R2
9701
PPP6R2
protein phosphatase 6 regu...
PRMT3
10196
PRMT3
protein arginine methyltra...
PSMD11
5717
PSMD11
proteasome 26S subunit, no...
PSMD13
5719
PSMD13
proteasome 26S subunit, no...
PTGDS
5730
PTGDS
prostaglandin D2 synthase ...
PTGER4
5734
PTGER4
prostaglandin E receptor 4...
PTGS1
5742
PTGS1
prostaglandin-endoperoxide...
PTPN9
5780
PTPN9
protein tyrosine phosphata...
PTPRO
5800
PTPRO
protein tyrosine phosphata...
PUS7
54517
PUS7
pseudouridine synthase 7 [...
PWWP2B
170394
PWWP2B
PWWP domain containing 2B ...
RASA3
22821
RASA3
RAS p21 protein activator ...
RBM19
9904
RBM19
RNA binding motif protein ...
RHEBL1
121268
RHEBL1
RHEB like 1 [Source:HGNC S...
RHOC
389
RHOC
ras homolog family member ...
RNASEH2B
79621
RNASEH2B
ribonuclease H2 subunit B ...
RNF11
26994
RNF11
ring finger protein 11 [So...
RPL7L1
285855
RPL7L1
ribosomal protein L7 like ...
S1PR2
9294
S1PR2
sphingosine-1-phosphate re...
SCAMP3
10067
SCAMP3
secretory carrier membrane...
SCHIP1
29970
SCHIP1
schwannomin interacting pr...
SCRIB
23513
SCRIB
scribble planar cell polar...
SH2B3
10019
SH2B3
SH2B adaptor protein 3 [So...
SLC16A3
9123
SLC16A3
solute carrier family 16 m...
SLC25A19
60386
SLC25A19
solute carrier family 25 m...
SLC27A4
10999
SLC27A4
solute carrier family 27 m...
SLC30A7
148867
SLC30A7
solute carrier family 30 m...
SLC39A12
221074
SLC39A12
solute carrier family 39 m...
SLC39A13
91252
SLC39A13
solute carrier family 39 m...
SNAPC2
6618
SNAPC2
small nuclear RNA activati...
SNAPC3
6619
SNAPC3
small nuclear RNA activati...
SNRNP27
11017
SNRNP27
small nuclear ribonucleopr...
SNRPB
6628
SNRPB
small nuclear ribonucleopr...
SNX24
28966
SNX24
sorting nexin 24 [Source:H...
SREK1
140890
SREK1
splicing regulatory glutam...
STT3B
201595
STT3B
STT3 oligosaccharyltransfe...
STX4
6810
STX4
syntaxin 4 [Source:HGNC Sy...
STYX
6815
STYX
serine/threonine/tyrosine ...
SYNC
81493
SYNC
syncoilin, intermediate fi...
TCF3
6929
TCF3
transcription factor 3 [So...
TFDP2
7029
TFDP2
transcription factor Dp-2 ...
THAP8
199745
THAP8
THAP domain containing 8 [...
TLK2
11011
TLK2
tousled like kinase 2 [Sou...
TMEM110
375346
STIMATE
STIM activating enhancer [...
TMEM134
80194
TMEM134
transmembrane protein 134 ...
TMEM62
80021
TMEM62
transmembrane protein 62 [...
TMEM74
157753
TMEM74
transmembrane protein 74 [...
TMEM86B
255043
TMEM86B
transmembrane protein 86B ...
TNFRSF4
7293
TNFRSF4
TNF receptor superfamily m...
TNFSF14
8740
TNFSF14
TNF superfamily member 14 ...
TRIM8
81603
TRIM8
tripartite motif containin...
TSPAN15
23555
TSPAN15
tetraspanin 15 [Source:HGN...
TSTD2
158427
TSTD2
thiosulfate sulfurtransfer...
TTC19
54902
TTC19
tetratricopeptide repeat d...
TTC9B
148014
TTC9B
tetratricopeptide repeat d...
TTLL1
25809
TTLL1
TTL family tubulin polyglu...
TUBB
203068
TUBB
tubulin beta class I [Sour...
UBE2G2
7327
UBE2G2
ubiquitin conjugating enzy...
UBXN8
7993
UBXN8
UBX domain protein 8 [Sour...
UFSP2
55325
UFSP2
UFM1 specific peptidase 2 ...
UNC45A
55898
UNC45A
unc-45 myosin chaperone A ...
UQCRFS1
7386
UQCRFS1
ubiquinol-cytochrome c red...
USMG5
84833
ATP5MK
ATP synthase membrane subu...
VDAC2
7417
VDAC2
voltage dependent anion ch...
WDR46
9277
WDR46
WD repeat domain 46 [Sourc...
WDR54
84058
WDR54
WD repeat domain 54 [Sourc...
ZBTB7B
51043
ZBTB7B
zinc finger and BTB domain...
ZCCHC24
219654
ZCCHC24
zinc finger CCHC-type cont...
ZEB1
6935
ZEB1
zinc finger E-box binding ...
ZNF281
23528
ZNF281
zinc finger protein 281 [S...
ZNF346
23567
ZNF346
zinc finger protein 346 [S...
ZNRF1
84937
ZNRF1
zinc and ring finger 1 [So...
ZSWIM2
151112
ZSWIM2
zinc finger SWIM-type cont...
Version history
7.3: Moved to ImmuneSigDB sub-collection.
See
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. Please note that certain gene sets have special access terms.