Human Gene Set: GSE12839_CTRL_VS_IL12_TREATED_PBMC_DN


Standard name GSE12839_CTRL_VS_IL12_TREATED_PBMC_DN
Systematic name M441
Brief description Genes down-regulated in peripheral blood monocytes (PBMC): control versus IL-12 stimulation.
Full description or abstract The cytokine interleukin-12 (IL-12) is known to play a central role in adaptive and innate immunity. We employed microarray analysis of IL-12 induced gene expression to provide further insights into its effects on immune response.
Collection C7: Immunologic Signature
      IMMUNESIGDB: ImmuneSigDB
Source publication Pubmed 19001140   Authors: Watford WT,Hissong BD,Durant LR,Yamane H,Muul LM,Kanno Y,Tato CM,Ramos HL,Berger AE,Mielke L,Pesu M,Solomon B,Frucht DM,Paul WE,Sher A,Jankovic D,Tsichlis PN,O'Shea JJ
Exact source GSE12839_2401_200_DN
Related gene sets (show 1 additional gene sets from the source publication)

(show 282 gene sets from the same authors)
External links
Filtered by similarity ?
Source species Homo sapiens
Contributed by Jernej Godec (Dana-Farber Cancer Institute)
Source platform or
identifier namespace		 HUMAN_GENE_SYMBOL
Dataset references (show 1 datasets)
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 127 genes
Gene families ? Categorize these 127 genes by gene family
Show members (show 200 source identifiers mapped to 127 genes)
Version history 7.3: Moved to ImmuneSigDB sub-collection.

See MSigDB license terms here. Please note that certain gene sets have special access terms.