Human Gene Set: GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP
Standard name
GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP
Systematic name
M3138
Brief description
Genes up-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] versus macrophages cultured with M-CSF [GeneID=1435], IFNG [GeneID=3458] and Pam3Cyc.
Full description or abstract
Gene expression analysis of freshly isolated CD14+ human monocytes and monocytes cultured in the presence or absence of interferon (IFN) -gamma for 24 h and then stimulated with Pam3Cys, a Toll-like receptor (TLR) 2 ligand, for 6 h. Results provide insight into mechanisms by which IFN-gamma reprograms early macrophage differentiation and subsequent response to TLR ligands.
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