Human Gene Set: GOMF_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY

For the Mouse gene set with the same name, see GOMF_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY

Standard name GOMF_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY
Systematic name M17485
Brief description Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions. [GOC:kd, GOC:mah, PMID:23303910, PMID:27218782]
Full description or abstract  
Collection C5: Ontology
      GO: Gene Ontology
            GO:MF: GO Molecular Function
Source publication  
Exact source GO:0005085
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0005085
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Source species Homo sapiens
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
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Version history 2024.1.Hs: Updated to GO Release 2024-04-24.

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