Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+. [EC:2.3.1.86]
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C5: Ontology GO: Gene Ontology GO:MF: GO Molecular Function